Identification | Back Directory | [Name]
alpha-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethyl]-omega-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]poly(oxy-1,2-ethanediyl) | [CAS]
326003-46-7 | [Synonyms]
326003-46-7 Mal-amido-PEG16-NHS Mal-amido-PEG24-NHS Mal-amido-PEG12-NHS ester Maleimide-NH-PEG16-CH2CH2COONHS Ester MALEIMIDE-NH-PEG24-CH2CH2COONHS ESTER Maleimidopropionyl-PEG24-CH2CH2COONHS Ester Maleimidopropionyl-PEG16-CH2CH2COONHS Ester alpha-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethyl]-omega-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]poly(oxy-1,2-ethanediyl) | [Molecular Formula]
C62H111N3O31 | [MDL Number]
MFCD11041148 | [MOL File]
326003-46-7.mol | [Molecular Weight]
1394.55 |
Chemical Properties | Back Directory | [InChI]
InChI=1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22) | [InChIKey]
TZPDZOJURBVWHS-UHFFFAOYSA-N | [SMILES]
C(N1C(C=CC1=O)=O)CC(=O)NCCO{-}CC{+n}OCCC(=O)ON1C(CCC1=O)=O |
Hazard Information | Back Directory | [Description]
Mal-amido-PEG24-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. |
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