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756525-93-6

756525-93-6 Structure

756525-93-6 Structure
IdentificationBack Directory
[Name]

alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol)
[CAS]

756525-93-6
[Synonyms]

Mal-PEG8-NHS
Mal-NH-PEG8-NHS
Mal-amide-PEG8-NHS
Mal-amido-PEG8-NHS
Maleimide-PEG8-NHS
Mal-NH-PEG8-NHS ester
Maleimide-PEG8-NHS ester
MAL-NH-PEG8-CH2CH2COONHS
Mal-amido-PEG8-NHS ester
Maleimide-PEG8-succinimidyl ester
Maleimide PEG8 succinimidyl ester
Maleimide-NH-PEG8-CH2CH2COONHS Ester
Maleimidopropionyl-PEG8-CH2CH2COONHS Ester
α-MaleiMidopropionyl-ω-succiniMidyl-8(ethylene glycol)
alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol)
N-[27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic acid 2,5-dioxo-1-pyrrolidinyl ester
4,7,10,13,16,19,22,25-Octaoxa-28-azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C30H47N3O15
[MDL Number]

MFCD11041144
[MOL File]

756525-93-6.mol
[Molecular Weight]

689.71
Chemical PropertiesBack Directory
[density ]

1.30±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

DMSO : ≥ 100 mg/mL (144.99 mM)
[form ]

powder
[pka]

15.01±0.46(Predicted)
[color ]

Light yellowish
[InChIKey]

MTPWCXBUZLEBDD-UHFFFAOYSA-N
[SMILES]

C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
[WGK Germany ]

3
[HS Code ]

2928009090
Hazard InformationBack Directory
[Description]

Mal-amido-PEG8-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Uses]

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 39.2 angstroms.
[reaction suitability]

reaction type: Pegylations
reagent type: cross-linking reagent
[IC 50]

PEGs; Alkyl/ether
Spectrum DetailBack Directory
[Spectrum Detail]

alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol)(756525-93-6)1HNMR
alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol)(756525-93-6)1HNMR
alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol)(756525-93-6)13CNMR
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