| Identification | More | [Name]
1,1,3,3-Tetramethyldisiloxane | [CAS]
3277-26-7 | [Synonyms]
1,1,3,3-TETRAMETHYLDISILOXANE
BIS(DIMETHYLSILYL) ETHER
SILOXANE HSI2
TETRAMETHYLDISILOXANE
(CH3)2HSiOSiH(CH3)2
1,1,3,3-tetramethyl-disiloxan
1,3-Dihydrotetramethyldisiloxane
Bis(dimethylsilyl) oxide
bis(dimethylsilyl)oxide
CT2030
Dimethylsilyl ether
dimethylsilylether
Disiloxane, 1,1,3,3-tetramethyl-
sym-Tetramethyldisiloxane
1,1,3,3-TETRAMETHYLDISILOXANE,WACKER QUALITY
Tetramethyldisiloxan
1,1,3,3,-TETRAMETHYLDISLOXANE
1,1,3,3-TETRAMETHYLDISILOXANE 97+%
1,1,3,3-Tetramethyl-1,3-dihydrodisiloxane
1,1,3,3-Tetramethyl-1,3-disiloxane | [EINECS(EC#)]
221-906-4 | [Molecular Formula]
C4H14OSi2 | [MDL Number]
MFCD00008256 | [Molecular Weight]
134.32 | [MOL File]
3277-26-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless or yellowish transparent liquid | [Melting point ]
<-78°C | [Boiling point ]
70-71 °C (lit.) | [density ]
0.76 g/mL at 25 °C(lit.)
| [vapor pressure ]
250 hPa (20 °C) | [refractive index ]
n20/D 1.370(lit.)
| [Fp ]
14 °F
| [storage temp. ]
2-8°C
| [solubility ]
soluble in Chloroform | [form ]
liquid | [pka]
11.9[at 20 ℃] | [color ]
colorless | [Specific Gravity]
0.757 | [explosive limit]
0.8-62.9%(V) | [Water Solubility ]
DECOMPOSES | [Hydrolytic Sensitivity]
3: reacts with aqueous base | [Sensitive ]
Moisture Sensitive | [BRN ]
1733364 | [InChI]
1S/C4H14OSi2/c1-6(2)5-7(3)4/h6-7H,1-4H3 | [InChIKey]
NVYQDQZEMGUESH-UHFFFAOYSA-N | [SMILES]
C[SiH](C)O[SiH](C)C | [LogP]
-0.38-4.5 at 20-25℃ | [CAS DataBase Reference]
3277-26-7(CAS DataBase Reference) | [NIST Chemistry Reference]
((CH3)2SiH)2O(3277-26-7) | [EPA Substance Registry System]
3277-26-7(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
The hydrosilylation of siloxanes was carried out in a Pyrex temperature-controlled reactor. The catalyst was added to the reactor. A pre-prepared mixture of octamethylcyclotetrasiloxane, hydrogen, and vinylsiloxane was added in a 2:3:1 ratio. The reactor was evacuated and the mixture was kept at a constant temperature with stirring. Platinum was concentrated in C(4.2–17.0) × 10⁻⁵ mol g⁻¹ polymethyl sulfide. The mixture was heated at 70°C for 1.5 hours. The title compound, 1,1,3,3-tetramethyldisiloxane, was purified by silica gel column chromatography.  Figure 1, Synthetic route of 1,3,3-tetramethyldisiloxane |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS02 | [Signal word ]
Danger | [Hazard statements ]
H225 | [Precautionary statements ]
P210-P233-P240-P241-P242-P243 | [Hazard Codes ]
F | [Risk Statements ]
R11:Highly Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
R16:Explosive when mixed with oxidizing substances. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S9:Keep container in a well-ventilated place .
S33:Take precautionary measures against static discharges .
S29:Do not empty into drains . | [RIDADR ]
UN 2924 3/PG 2
| [WGK Germany ]
3
| [RTECS ]
JN1000000
| [F ]
10-21 | [Autoignition Temperature]
240 °C | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29310095 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Flam. Liq. 2 |
| Questions and Answers (Q&A) | Back Directory | [Description]
1, 1, 3, 3-Tetramethyldisiloxane is a kind of siloxane derivative, and can be used as a monomer for the preparation of silicone polymers or silicone resins. It is used as an intermediate for preparing other organosilicon compounds. It is also used in non-aqueous polymer preparation as well as a laboratory reagent. In organic synthesis, it finds an application as an effective reducing agent in platinum-catalyzed reduction of carboxamides to amines as well as in the Au/TiO2-catalyzed hydrosilylation of carbonyl compounds (e.g., reduction of aldehydes or ketones) relative to monohydrosilanes. It can also enable a direct bromination of carboxylic acids in the presence of indium bromide (InBr3) as catalyst.
| [References]
https://www.alfa.com/en/catalog/B23697/
http://www.organic-chemistry.org/chemicals/reductions/tetramethyldisiloxane-TMDSO.shtm
https://www.infona.pl/resource/bwmeta1.element.elsevier-722236cc-df38-37aa-bbed-029ec07d525f
|
| Hazard Information | Back Directory | [Chemical Properties]
Colorless or yellowish transparent liquid | [Application]
1, 1, 3, 3-Tetramethyldisiloxane is a kind of siloxane derivative, and can be used as a monomer for the preparation of silicone polymers or silicone resins. It is used as an intermediate for preparing other organosilicon compounds. It is also used in non-aqueous polymer preparation as well as a laboratory reagent. In organic synthesis, it finds an application as an effective reducing agent in platinum-catalyzed reduction of carboxamides to amines as well as in the Au/TiO2-catalyzed hydrosilylation of carbonyl compounds (e.g., reduction of aldehydes or ketones) relative to monohydrosilanes. It can also enable a direct bromination of carboxylic acids in the presence of indium bromide (InBr3) as catalyst.
| [Uses]
1, 1, 3, 3-Tetramethyldisiloxane is a kind of siloxane derivative, and can be used as a monomer for the preparation of silicone polymers or silicone resins. It is used as an intermediate for preparing other organosilicon compounds. It is also used in non-aqueous polymer preparation as well as a laboratory reagent. In organic synthesis, it finds an application as an effective reducing agent in platinum-catalyzed reduction of carboxamides to amines as well as in the Au/TiO2-catalyzed hydrosilylation of carbonyl compounds (e.g., reduction of aldehydes or ketones) relative to monohydrosilanes. It can also enable a direct bromination of carboxylic acids in the presence of indium bromide (InBr3) as catalyst.
| [Uses]
1. Synthesis of polysiloxane containing faculties end groups.
2. Can be used for the preparation of high performance organic silicone surfactants.
3. Applicable to the production of many products, such as addition silicon rubber, silica gel, Hydrogenpolysiloxane and plastic, resin modifier, dendrite polymer special additives, etc. | [Flammability and Explosibility]
Highlyflammable | [reaction suitability]
reagent type: reductant | [Purification Methods]
1,Possible impurity is 1,1,5,5-tetramethyl-3-trimethylsiloxytrisiloxane b 154-155o/733mm. Fractionate it, collect fractions boiling below 80o and re-fractionate it. Its purity can be analysed by alkaline hydrolysis and measuring the volume of H2 liberated followed by gravimetric estimation of silica in the hydrolysate. It is unchanged when stored in glass containers in the absence of moisture for 2-3 weeks. Small amounts of H2 are liberated on long storage. Care should be taken when opening a container due to pressure developed. [Speier et al. J Am Chem Soc 79 974 1958, Emeléus & Smythe J Chem Soc 609 1958, IR: Kriegsmann Z Anorg Chem 299 78 1959, Beilstein 4 IV 3991.] | [Toxicity evaluation]
1,1,3,3-Tetramethyldisiloxane is irritating to the eyes and upper respiratory tract. Ingestion can be fatal.
| [Toxics Screening Level]
The ITSL for tetramethyldihydrogendisiloxane is being established at this time as 120 μg/m3 with annual averaging. |
| Spectrum Detail | Back Directory | [Spectrum Detail]
1,1,3,3-Tetramethyldisiloxane(3277-26-7)MS
1,1,3,3-Tetramethyldisiloxane(3277-26-7)1HNMR
1,1,3,3-Tetramethyldisiloxane(3277-26-7)13CNMR
1,1,3,3-Tetramethyldisiloxane(3277-26-7)IR1
1,1,3,3-Tetramethyldisiloxane(3277-26-7)Raman
|
| Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
1,1,3,3-Tetramethyldisiloxane, 97%(3277-26-7) | [Alfa Aesar]
1,1,3,3-Tetramethyldisiloxane, 97%(3277-26-7) | [Sigma Aldrich]
3277-26-7(sigmaaldrich) | [TCI AMERICA]
1,1,3,3-Tetramethyldisiloxane,>97.0%(GC)(3277-26-7) |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|