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34429-70-4

34429-70-4 Structure

34429-70-4 Structure
IdentificationBack Directory
[Name]

TIRANDAMYCIN
[CAS]

34429-70-4
[Synonyms]

TIRANDAMYCIN
tirandamycin A
3-[(1E,2E,4E,6R)-1-Hydroxy-4-methyl-6-[(1S,4α,6S)-1,2α,7α-trimethyl-5-oxo-3,9,10-trioxatricyclo[4.3.1.02,4]decan-8β-yl]-2,4-heptadien-1-ylidene]-2,4-pyrrolidinedione
[Molecular Formula]

C22H27NO7
[MOL File]

34429-70-4.mol
[Molecular Weight]

417.45
Chemical PropertiesBack Directory
[Boiling point ]

639.1±55.0 °C(Predicted)
[density ]

1.307±0.06 g/cm3(Predicted)
[pka]

6?+-.0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties[1][2].
[Definition]

ChEBI: Tirandamycin is an oxacycle.
[IC 50]

Amebae
[References]

[1] Avelina Espinosa, et al. Antiamoebic properties of the actinomycete metabolites echinomycin A and tirandamycin A. Parasitol Res. 2012 Dec;111(6):2473-7. DOI:10.1007/s00436-012-3019-2
[2] H Hagenmaier, et al. Metabiolic products of microorganisms. Tirandamycin B(author's transl). Arch Microbiol. 1976 Aug;109(1-2):65-74. DOI:10.1007/BF00425114
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