| Identification | More | [Name]
DL-METHIONINE METHYLSULFONIUM CHLORIDE | [CAS]
3493-12-7 | [Synonyms]
(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE
CITRIN
DL-(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE
DL-METHIONINE METHYLSULFONIUM CHLORIDE
DL-METHYLMETHIONINE SULFONIUMCHLORIDE
METHYL-METHIONINE SULPHONIUM CHLORIDE
MMS
S-METHYL-DL-METHIONINE-SULFONIUMCHLORIDE
S-METHYLMETHIONINESULFONIUM CHLORIDE
VITAMIN U
VITAMIN U CHLORIDE
(3-amino-3-carboxypropyl)dimethyl-,chloride,(+/-)-sulfoniu
Vitaminuchloride,99%
(±)-(3-amino-3-carboxypropyl)dimethylsulphonium chloride
methionylmethylsulfonium chloride
SULFONIUM,(3-AMINO-3-CARBOXYPROPYL)DIMETHYL-,CHLORIDE
DL-methionine-S-methyl-sulfonium chloride
(3-Amino-3-carboxypropyl)dimethyl sulfonium chloride, Methyl-methionine sulphonium chloride, MMS, Vitamin U | [EINECS(EC#)]
222-484-4 | [Molecular Formula]
C6H14ClNO2S | [MDL Number]
MFCD00031700 | [Molecular Weight]
199.7 | [MOL File]
3493-12-7.mol |
| Questions And Answer | Back Directory | [Preparation]
1. Methionine is reacted with chloromethane under pressure and then filtered to obtain a DL-METHIONINE METHYLSULFONIUM CHLORIDE solution; 2. The DL-METHIONINE METHYLSULFONIUM CHLORIDE solution prepared in step 1 is filtered and concentrated under reduced pressure to obtain a powder; 3. The powder from step 2 is added to methanol and slurryed, then cooled until crystallization occurs, forming a DL-METHIONINE METHYLSULFONIUM CHLORIDE mixture; 4. The mixture is placed in a centrifuge, and the filter cake is washed with methanol. The filter cake is discharged when no continuous droplets flow out; 5. The filter cake is dried to obtain pharmaceutical-grade DL-METHIONINE METHYLSULFONIUM CHLORIDE. |
| Hazard Information | Back Directory | [Description]
DL-Methionine methylsulfonium chloride, also named Vitamin U, is a powerful antioxidant. It is a sulfur derivative substance. Graviola leaves contain much vitamin U[1]. Vitamin U have unique antioxidant effect. It could prevents Galactosamine-induced gastric damage and protects pentylenetetrazole-induced brain damage in rats[2-3]. | [Uses]
DL-Methionine Methylsulfonium Chloride is a compound comprised of γ-glutamyl peptide and amino acid that have a sucrose-like taste. | [Biochem/physiol Actions]
S-Methionine methylsulfonium (SMMS) chloride is a derivative of methionine metabolism in some plants. SMMS has potent therapeutic effects on gastrointestinal ulceration potentially via its ability to promote dermal fibroblast migration and growth. | [storage]
Store at -20°C | [References]
[1] Choi E, et al. Increased Intestinal Absorption of Vitamin U in Steamed Graviola Leaf Extract Activates Nicotine Detoxification. Nutrients, 2019; 11.
[2] Topaloglu D, et al. Gastroprotective effect of vitamin U in D-galactosamine-induced hepatotoxicity. Journal of Biochemical and Molecular Toxicology, 2022; 36: e23124.
[3] Bayrak G, et al. The protective effect of vitamin U on pentylenetetrazole-induced brain damage in rats, 2022; 36: e23169. |
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