| Identification | More | [Name]
Sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium | [CAS]
3599-32-4 | [Synonyms]
1H-BENZ[E]INDOLIUM, 2-[7-[1,1-DIMETHYL-3-(4-SULFOBUTYL)BENZ[E]INDOLIN-2-YLIDENE]-1,3,5-HEPTATRIENYL]-1,1-DIMETHYL-3-(4-SULFOBUTYL)-, HYDROXIDE, INNER SALT, SODIUM SALT
1H-BENZ[E]INDOLIUM, 2-[7-[1,3-DIHYDRO-1,1-DIMETHYL-3-(4-SULFOBUTYL)-2H-BENZ[E]INDOL-2-YLIDENE]-1,3,5-HEPTATRIENYL]-1,1-DIMETHYL-3-(4-SULFOBUTYL)-, HYDROXIDE, INNER SALT, SODIUM SALT
1H-BENZ[E]INDOLIUM, 2-[7-[1,3-DIHYDRO-1,1-DIMETHYL-3-(4-SULFOBUTYL)-2H-BENZ[E]INDOL-2-YLIDENE]-1,3,5-HEPTATRIENYL]-1,1-DIMETHYL-3-(4-SULFOBUTYL)-, INNER SALT, SODIUM SALT
4-(2-[7-[1,1-DIMETHYL-3-(4-SULFO-BUTYL)-1H-BENZO[E]INDOL-2-YL]-HEPTA-2,4,6-TRIENYLIDENE]-1,1-DIMETHYL-BENZO[E]INDOLIUM-3-YL)-BUTANE-1-SULFONIC ACID SODIUM SALT
4,5-BENZOINDOTRICARBOCYANINE
BIS-[1-(4-SULFOBUTYL)-3,3-DIMETHYL-4,5-BENZOINDOLINYLIDEN-2]-HEPTAMETHINECYANINE-BETAINE-SODIUM SALT (INDOCYANINEGREEN, CARDIOGREEN)
CARDIOGREEN
FOXGREEN
HWD INDOCYANINE GREEN
ICG
IC GREEN
INDOCYANINE GREEN
INDOCYANIN GREEN
IR-125
NK 2611
NK 2612
UJOVIRIDIN
)-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,
,innersalt,sodiumsalt(9ci)
-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,so | [EINECS(EC#)]
222-751-5 | [Molecular Formula]
C43H47N2NaO6S2 | [MDL Number]
MFCD00013078 | [Molecular Weight]
774.96 | [MOL File]
3599-32-4.mol |
| Chemical Properties | Back Directory | [Appearance]
green to brown crystals or crystalline powder | [Melting point ]
235 °C
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
H2O: soluble1mg/mL | [form ]
Powder | [color ]
Green-bronze | [Water Solubility ]
slightly soluble | [ex/em]
786/820nm (Methanol) | [ε(extinction coefficient)]
≥115 at 386-396nm in water
≥2000 at 774-784nm in water
≥900 at 712-722nm in water | [Φ(quantum yield)]
0.09 | [Merck ]
4962 | [BRN ]
4115884 | [InChIKey]
JDDBTPDPBRYGPQ-UHFFFAOYSA-N | [SMILES]
CC1(C(=[N+](CCCCS([O-])(=O)=O)C2C=CC3=CC=CC=C3C1=2)C=CC=CC=CC=C1C(C2C3=CC=CC=C3C=CC=2N1CCCCS(O)(=O)=O)(C)C)C.[NaH] | [LogP]
-0.290 | [CAS DataBase Reference]
3599-32-4(CAS DataBase Reference) | [EPA Substance Registry System]
3599-32-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
DE3150000
| [HS Code ]
32129000 | [Safety Profile]
Poison by intravenous
route. When heated to decomposition it
emits very toxic fumes of SOx, Na2O, and
NOx. | [Hazardous Substances Data]
3599-32-4(Hazardous Substances Data) | [Toxicity]
LD50 intravenous in mouse: 60mg/kg |
| Hazard Information | Back Directory | [Description]
Indocyanine Green (aka ICG, IC Green, Foxgreen) is used for reliable imaging and flow cytometry. This dye is water-soluble and pH-insensitive. The fluorescence of Indocyanine Green is not visible to the human eye but is readily detected by most imaging systems.
Indocyanine Green binds tightly to plasma proteins and becomes confined to the vascular system. The dye has a half-life of 150 to 180 sec and is removed from circulation exclusively by the liver to bile juice.
Indocyanine Green is used for detection of hepatocyte-like cells, determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography. | [Chemical Properties]
green to brown crystals or crystalline powder | [Uses]
A tricarbocyanine type of dye with infrared absorbing properties. Diagnostic aid (blood volume determination, cardiac output, hepatic function). | [Uses]
A tricarbocyanine type of dye with infrared absorbing properties. Diagnostic aid (blood volume determination, cardiac output, hepatic function). Dyes and metabolites. | [Uses]
In infrared photography; in preparation of Wratten filters. | [Brand name]
IC-Green
(Akorn). | [storage]
Store at -20°C | [Abs/Em Maxima]
787/819 nm | [Fluoresene quantum yield]
0.09 | [Extinction Coefficient]
232000 |
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