| Identification | More | [Name]
1,1,2-Trimethyl-1H-benz[e]indole | [CAS]
41532-84-7 | [Synonyms]
1,1,2-TRIMETHYL-1H-BENZ[E]INDOLE
1,1,2-TRIMETHYL-1H-BENZO[E]INDOLE
1,1,2-TRIMETHYLBENZ[E]INDOLE
1,1,2-TRIMETHYLBENZO[E]INDOLE
1,1,2-TRIMETHYLNAPHTHO[1,2-D]PYRROLE
1H-BENZO[E]INDOLE, 1,1,2-TRIMETHYL-
2,3,3-TRIMETHYL-3H-BENZ[E]INDOL
2,3,3-TRIMETHYL-3H-BENZO[E]INDOLE
2,3,3-TRIMETHYL-4,5-BENZO-3H-INDOLE
2,3,3-TRIMETHYL-4,5-BENZOINDOLENINE
2,3,3-TRIMETHYLBENZO[E]INDOLENINE
2,3,3-TRIMETHYLBENZOINDOLENINE
2,3,3-TRIMETHYLNAPHTO[1,2-D]PYRROLE
AKOS BBS-00006363
TMBI
1,1,2-trimethyl-1h-benz[e]indol
1,1,2-TRIMEHTYL-1H-BENZ[E]INDOLE
2,3,3-Trimethyl-1H-Benzo(E)Indole
1,2,2-Trimethyl-1H-benz[e]indole
2,3,3-trimethylnaphtho[1,2-d]pyrrole | [EINECS(EC#)]
255-429-8 | [Molecular Formula]
C15H15N | [MDL Number]
MFCD00082627 | [Molecular Weight]
209.29 | [MOL File]
41532-84-7.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow to brown crystalline powder | [Melting point ]
111-117 °C | [Boiling point ]
338.66°C (rough estimate) | [density ]
0.7
| [refractive index ]
1.5720 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
insoluble (20°C) | [form ]
Crystalline Powder | [pka]
5.77±0.40(Predicted) | [color ]
Yellow to brown | [Water Solubility ]
insoluble (20 ºC) | [Detection Methods]
HPLC,NMR | [BRN ]
153709 | [InChI]
InChI=1S/C15H15N/c1-10-15(2,3)14-12-7-5-4-6-11(12)8-9-13(14)16-10/h4-9H,1-3H3 | [InChIKey]
WJZSZXCWMATYFX-UHFFFAOYSA-N | [SMILES]
N1C2=C(C3=CC=CC=C3C=C2)C(C)(C)C=1C | [CAS DataBase Reference]
41532-84-7(CAS DataBase Reference) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
1H-Benz[e]indole, 1,1,2-trimethyl- (41532-84-7) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R45:May cause cancer. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S53:Avoid exposure-obtain special instruction before use .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow to brown crystalline powder | [Uses]
1,1,2-Trimethyl-1H-benzo[e]indole can be used as an indole pH fluorescent probe and can be used for intracellular pH detection and cell marking. It can also be used as a novel nanocarrier-based near-infrared optical probes for in-vivo tumor imaging. | [Synthesis]
Isopropyl methyl ketone (9.00 g, 0.1 mol) was added to a solution of 2-naphthylhydrazine hydrochloride (15.80 g, 0.1 mol) in glacial acetic acid (100 mL). The mixture was stirred for 0.5 h at 20 °C and refluxed for 6 h. Then, the reaction mixture was poured onto ice and neutralized with sodium carbonate, a precipitate formed was collected by filtration. The yield was 19.8 g (95%).
![1,1,2-Trimethyl-1H-benz[e]indole](/NewsImg/2023-12-07/6383755462801426852705277.jpg "1,1,2-Trimethyl-1H-benz[e]indole") | [References]
[1] Russian Chemical Bulletin, 2016, vol. 65, # 11, p. 2722 - 2728
[2] Izv. Akad. Nauk, Ser. Khim., 2016, # 11, p. 2722 - 2728,7 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
1,1,2-Trimethyl-1H-benz[e]indole(41532-84-7)MS
1,1,2-Trimethyl-1H-benz[e]indole(41532-84-7)1HNMR
1,1,2-Trimethyl-1H-benz[e]indole(41532-84-7)13CNMR
1,1,2-Trimethyl-1H-benz[e]indole(41532-84-7)IR1
1,1,2-Trimethyl-1H-benz[e]indole(41532-84-7)IR2
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| Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
1,1,2-Trimethyl-1H-benz[e]indole, 96%(41532-84-7) | [Alfa Aesar]
1,1,2-Trimethyl-1H-benz[e]indole, 97%(41532-84-7) | [Sigma Aldrich]
41532-84-7(sigmaaldrich) | [TCI AMERICA]
2,3,3-Trimethyl-4,5-benzo-3H-indole,>97.0%(T)(41532-84-7) |
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