ChemicalBook--->CAS DataBase List--->36394-75-9

36394-75-9

36394-75-9 Structure

36394-75-9 Structure
IdentificationMore
[Name]

(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
[CAS]

36394-75-9
[Synonyms]

AP-CL
O-ACETYL-L-LACTYL CHLORIDE
(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
(S)-2-ACETOXYPROPIONYL CHLORIDE
S-ACETOXYPROPIONYL CHLORIDE
(S)-(-)-O-ACETYLLACTOYL CHLORIDE
2-Acetoxy propionyl chloride
L-(-)-2-ACETOXYPROPIONYL CHLORIDE
(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE 97+%
O-Acetyl-L-lactyl chloride, AP-Cl
(S)-2-Acetoxypropionic acid chloride
[(2S)-2-Acetoxypropionyl] chloride
Acetic acid (S)-1-(chlorocarbonyl)ethyl ester
Acetic acid (S)-1-methyl-2-oxo-2-chloroethyl ester
Mosandl reagent
[EINECS(EC#)]

420-610-4
[Molecular Formula]

C5H7ClO3
[MDL Number]

MFCD00145252
[Molecular Weight]

150.56
[MOL File]

36394-75-9.mol
Chemical PropertiesBack Directory
[alpha ]

-31o (C=4 IN CHLOROFORM)
[Boiling point ]

50 °C5 mm Hg(lit.)
[density ]

1.189 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.423(lit.)
[Fp ]

>230 °F
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Sparingly)
[form ]

clear liquid
[color ]

Colorless to Light yellow
[Specific Gravity]

1.19
[Optical Rotation]

[α]20/D 31°, c = 4 in chloroform
[BRN ]

1722943
[Stability:]

Hygroscopic, Moisture sensitive
[InChI]

InChI=1S/C5H7ClO3/c1-3(5(6)8)9-4(2)7/h3H,1-2H3/t3-/m0/s1
[InChIKey]

ALHZEIINTQJLOT-VKHMYHEASA-N
[SMILES]

C(Cl)(=O)[C@@H](OC(C)=O)C
[CAS DataBase Reference]

36394-75-9(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H302-H314-H317
[Precautionary statements ]

P261-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 3265 8/PG 2
[WGK Germany ]

3
[F ]

10-21
[REACH Registrations]

Active
[HazardClass ]

8
[PackingGroup ]

III
[HS Code ]

2918199890
[Storage Class]

8A - Combustible corrosive hazardous materials
[Hazard Classifications]

Acute Tox. 4 Oral
Skin Corr. 1B
Skin Sens. 1
Hazard InformationBack Directory
[Uses]

Frequently used chiral building block. Also used to resolve a bicyclic α-hydroxylactone and to prepare chiral phosphonates used in an enantiomeric excess assay of unprotected amino acids. Useful chiral derivatizing agent.
[Purification Methods]

It is moisture sensitive and is hydrolysed to the corresponding acid. Check the IR spectrum. If the OH band above 3000cm -1 is too large and broad then the mixture should be refluxed with pure acetyl chloride for 1hour, evaporated and distilled under reduced pressure. [Julia & Sans J Chromatographic Sci 17 651 1979, Dolittle & Heath J Org Chem 49 5041 1984, Beilstein 3 II 189.]
Spectrum DetailBack Directory
[Spectrum Detail]

(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE(36394-75-9)1HNMR
(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE(36394-75-9)IR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

36394-75-9(sigmaaldrich)
[TCI AMERICA]

(S)-(-)-2-Acetoxypropionyl Chloride,>97.0%(GC)(T)(36394-75-9)
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