| Identification | Back Directory | [Name]
8-SHOGAOL | [CAS]
36700-45-5 | [Synonyms]
8-ShogaoI
8-SHOGAOL
1-(4-Hydroxy-3-methoxyphenyl)-4-dodecen-3-one
4-Dodecen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-
(E)-1-(4-hydroxy-3-methoxyphenyl)dodec-4-en-3-one | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C19H28O3 | [MDL Number]
MFCD21333718 | [MOL File]
36700-45-5.mol | [Molecular Weight]
304.424 |
| Chemical Properties | Back Directory | [Boiling point ]
452.3±35.0 °C(Predicted) | [density ]
1.013±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in chloroform and methanol; | [form ]
liquid | [pka]
10.01±0.20(Predicted) | [color ]
Colorless - yellowish viscous | [Water Solubility ]
insoluble in water |
| Hazard Information | Back Directory | [Uses]
8-?Shogaol is a component of ginger (Zingiber officinale) and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor. | [Definition]
ChEBI: [8]-Shogaol is a monomethoxybenzene, an enone and a member of phenols. | [in vivo]
[8]-Shogaol (10 mg/kg, 30 mg/kg; ip; once daily for 10 days) reduces paw thickness and improves walking performance in a rat model of adjuvant-induced arthritis (AIA)[4].
| [target]
ROS | [IC 50]
COX-2: 17.5 μM (IC50) | [storage]
Store at -20°C |
|
|