| Identification | More | [Name]
QUAZEPAM CIV (200 MG) | [CAS]
36735-22-5 | [Synonyms]
,2-trifluoroethyl)-
2h-1,4-benzodiazepine-2-thione,7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2
dormalin
oniria
prosedar
quazepam
quazium
sch16134
QUAZEPAM CIV (200 MG)
2H-1,4-Benzodiazepine-2-thione
2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-
SELEPAM
7-Chloro-5-(2-fluorophenyl)-1，3-dihydro-1-(2，2，2-trifluoroethyl)-2H-1，4-benzodiazepine-2-thione
She-16134
7-Chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-1H-1,4-benzodiazepine-2(3H)-thione
Sch-161
7-Chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione | [EINECS(EC#)]
253-179-4 | [Molecular Formula]
C9H6N2S | [MDL Number]
MFCD00868025 | [Molecular Weight]
174.222 | [MOL File]
36735-22-5.mol |
| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
2933996500 | [Toxicity]
LD50 in mice (mg/kg): >1370 i.v., >5000 orally (Orgini); LD50 in male, female mice, rats (mg/kg): 845, 921, 3072, 2749 i.p. (Black) |
| Hazard Information | Back Directory | [Description]
Quazepam is a rapidly acting, short term hypnotic reported to exhibit a low
incidence of side effects. | [Originator]
Schering (USA) | [Uses]
Quazepam is a benzodiazepine derivative drug and is known to bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activty, motor coordination and memory. Quazepam is known to induce motor impairment and exerts hypnotic properties. Quazepam is often used for the treatment of insomina.
| [Definition]
ChEBI: Quazepam is a benzodiazepine. | [Brand name]
Doral (Questcor). | [General Description]
Quazepam (Doral) and its active metabolitesreportedly are relatively selective for the benzodiazepinemodulatory site on GABAA receptors with α1 subunitand are hypnotic agents. Quazepam is metabolized by oxidation to the 2-oxo compound and then N-dealkylation.Both metabolites are active; the first reportedly is the morepotent and selective. Thereafter, 3-hydroxylation and glucuronidationoccur. |
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LGM Pharma
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Sigma-Aldrich
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