| Identification | More | [Name]
RHODAMINE B ISOTHIOCYANATE | [CAS]
36877-69-7 | [Synonyms]
4(5)-RHODAMINE ISOTHIOCYANATE B
(9-(O-CARBOXYPHENYL)-6-(DIETHYL-AMINO)-3H-XANTHENE-3-YLINDENE)DIETHYL ISOTHIOCYANATE
RBITC
RHODAMINE B ISOTHIOCYANATE
RHODAMINE B ISOTHIOCYANATE-CELITE(R)
TETRAETHYLRHODAMINE ISOTHIOCYANATE
9-[2-carboxy-5(or6)-isothiocyanatophenyl]-3,6-bis(diethylamino)-xanthyliu
rhodamineisothiocyanate
9-[2-carboxy-5(or 6)-isothiocyanatophenyl]-3,6-bis(diethylamino)xanthylium chloride
RHODAMINE B ISOTHIOCYANATE >70%
RHODAMINE B ISOTHIOCYANATE, MIXTURE OF I SOMERS
RHODAMINE B ISOTHIOCYANATE, FOR FLUOR-ES C., MIX. OF ISOM.
RHODAMINE B ISOTHIOCYANATE CONJUGATION GRADE
Xanthylium, 9-2-carboxy-5(or 6)-isothiocyanatophenyl-3,6-bis(diethylamino)-, chloride
9-[2-Carboxy-5-isothiocyanatophenyl]-3,6-bis(diethylamino)xanthylium chloride | [EINECS(EC#)]
253-248-9 | [Molecular Formula]
C29H30N3O3S+ | [MDL Number]
MFCD03065941 | [Molecular Weight]
500.63 | [MOL File]
36877-69-7.mol |
| Chemical Properties | Back Directory | [Appearance]
solid | [storage temp. ]
2-8°C
| [solubility ]
methanol: soluble10mg/mL | [form ]
powder | [color ]
Green to dark green | [Stability:]
Stable, but may be sensitive to light or moisture. Store dark and dry. Incompatible with strong oxidizing agents. | [λmax]
555 nm | [InChI]
InChI=1S/C29H29N3O3S.ClH/c1-5-31(6-2)19-12-14-21-25(16-19)35-26-17-20(32(7-3)8-4)13-15-22(26)27(21)28-23(29(33)34)10-9-11-24(28)30-18-36;/h9-17H,5-8H2,1-4H3;1H | [InChIKey]
ASPXTKVHMNAXGJ-UHFFFAOYSA-N | [SMILES]
C1(=C2C=C/C(=[N+](\CC)/CC)/C=C2OC2C=C(N(CC)CC)C=CC1=2)C1=C(C(=O)O)C=CC=C1N=C=S.[Cl-] | [CAS DataBase Reference]
36877-69-7(CAS DataBase Reference) | [EPA Substance Registry System]
36877-69-7(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS07,GHS08 | [Signal word ]
Danger | [Hazard statements ]
H302+H312+H332-H315-H319-H334-H335 | [Precautionary statements ]
P261-P264-P280-P301+P312-P302+P352+P312-P305+P351+P338 | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R42:May cause sensitization by inhalation. | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3335 | [WGK Germany ]
3
| [F ]
8-10-21 | [TSCA ]
TSCA listed | [HS Code ]
29329990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3 |
| Questions And Answer | Back Directory | [Purity]
98% HPLC | [EX/EM]
552/583 nm；Solvent: ethanol; Tris-HCl buffer, pH 7 (at room temperature). This fluorescence is strongly quenched by quercetin[1].
|
| Hazard Information | Back Directory | [Description]
9-[2-Carboxy-5(or 6)-isothiocyanatophenyl]-3,6-bis(diethylamino)xanthylium, chloride is used in biomedical research as a fluorescent probe for detecting proteins and nucleic acids. It can also be employed in drug screening assays, imaging techniques, and studying cellular processes in cancer and neurological diseases. | [Chemical Properties]
solid | [Uses]
Rhodamine B isothiocyanate is a fluorescent probe. | [Application]
Rhodamine B isothiocyanate (RBITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy. It can be used in conjunction with immunohistochemistry for multi-labeling studies. It has also been used as an anterograde and retrograde tracer in neurons and in nanoparticles to detect apoptosis[1]. | [Definition]
ChEBI: The 5-isomer of rhodamine B isothiocyanate. | [General Description]
Rhodamine B isothiocyanate (RBITC) is a fluorescent dye. It acts as an anterograde and retrograde marker of retinal neurons in the adult rat. | [References]
[1] Ashraf El-Bindary , Taissir E.-S., Zeinab Anwar. (2021). Effect of silicon dioxide nanoparticles on the assessment of quercetin flavonoid using Rhodamine B Isothiocyanate dye. Journal of Molecular Liquids, 323, Article 114607. https://doi.org/10.1016/j.molliq.2020.114607 |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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