| Identification | More | [Name]
TRIETHYL 2-PHOSPHONOPROPIONATE | [CAS]
3699-66-9 | [Synonyms]
2-DIETHYLPHOSPHONOPROPIONIC ACID ETHYL ESTER
DIETHYL ETHOXYCARBONYLETHYL-PHOSPHONATE
ETHYL-2-(DIETHYLPHOSPHONO)PROPANOATE
TRIETHYL 2-PHOSPHONOPROPIONATE
Diethyl 1-(ethoxycarbonyl)ethanephosphonate~2-Phosphonopropionic acid triethyl ester
Triethyl2-phosphonopropionate,98%
2-phosphonopropionic acid triethyl ester
diethyl 1-(ethoxycarbonyl)ethanephosphonate
Triethyl 2-phosphonopropionate 97%
triethyl 2-phosphonoproprionate
Ethyl-2-(diethylphosphono)propanoate, 98 %
2-(Diethoxyphosphinyl)propanoic acid ethyl ester
2-Phosphonopropanoic acid triethyl ester | [EINECS(EC#)]
223-033-4 | [Molecular Formula]
C9H19O5P | [MDL Number]
MFCD00009159 | [Molecular Weight]
238.22 | [MOL File]
3699-66-9.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS LIQUID | [Melting point ]
161-164° | [Boiling point ]
143-144 °C12 mm Hg(lit.) | [density ]
1.111 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.431(lit.)
| [Fp ]
192 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Miscible with chloroform and methanol. | [form ]
Liquid | [color ]
Clear colorless | [Specific Gravity]
1.111 | [BRN ]
1786994 | [InChI]
InChI=1S/C9H19O5P/c1-5-12-9(10)8(4)15(11,13-6-2)14-7-3/h8H,5-7H2,1-4H3 | [InChIKey]
BVSRWCMAJISCTD-UHFFFAOYSA-N | [SMILES]
C(OCC)(=O)C(P(OCC)(OCC)=O)C | [CAS DataBase Reference]
3699-66-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
1993 | [WGK Germany ]
3
| [F ]
10 | [Hazard Note ]
Irritant | [HazardClass ]
3 | [HS Code ]
29319019 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS LIQUID | [Uses]
Triethyl 2-phosphonopropionate is used as a reactant in intramolecular conjugate addition for the synthesis of floresolide B, enantioselective synthesis of spiroindane di-methyl acetic acid and in stereo selective intramolecular Diels-Alder reactions. It plays an important role in Horner-Wadsworth-Emmons reactions and chemoenzymatic one-pot synthesis of gamma-butyrolactones. It is also used in the preparation of 3-[2]furyl-2-methyl-acrylic acid ethyl ester by reacting with furfural. | [Uses]
Triethyl 2-Phosphonopropionate is used in studies involving insecticides and their efficacy on various bacterium. Also act as inhibitors of Epstein-Bar virus transmission and infections. | [reaction suitability]
reaction type: C-C Bond Formation | [Purification Methods]
Purify it by fractional distillation with high reflux ratio, preferably using a spinning band column. [Kosolapoff & Powell J Am Chem Soc 72 4198 1950, Kresze et al. Justus Liebigs Ann Chem 756 112 1972, Beilstein 4 IV 3617.] |
|
|