ChemicalBook--->CAS DataBase List--->37025-55-1

37025-55-1

37025-55-1 Structure

37025-55-1 Structure
IdentificationBack Directory
[Name]

(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT
[CAS]

37025-55-1
[Synonyms]

Pabal
d(COMOT)
Depotocin
Carbansin
Duratocin
Lonactene
Carbetoxin
CARBETOCIN
Carbetocino
Carbetocinum
CARBAOXYTOCIN
Carbetocin Acetate
CARBETOCIN USP/EP/BP
Carbaoxytocin acetate salt
(BUTYRYL1,TYR(ME)2)-OXYTOCIN
M.W. 988.17 C45H69N11O12S
37025-55-1(Carbetocin acetate)
CARBETOCIN TRIFLUOROACETATE SALT
High purity CAS 37025-55-1 CARBETOCIN
DeaMino-2-O-Methyltyrosine-1-carbaoxytocin
Carbetocin Acetate, Carbetocino, Carbetocinum
(2-O-METHYLTYROSINE)-DE-AMINO-1-CARBAOXYTOCIN
Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Carbetocin, (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin
(BUTYRYL1,TYR(ME)2)-OXYTOCIN TRIFLUOROACETATE SALT
1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin
(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT
DURATOCIN;PABAL;LONACTENE;37025-55-1(CARBETOCIN ACETATE);
1-CARBAOXYTOCIN, 1-BUTANOIC ACID-2-(O-METHYL-L-TYROSINE)-
1-Carbaoxytocin,1-butanoic acid-2-(O-methyl-L-tyrosine)- (9CI)
Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2(Disulfide bond)
(Butyryl1,Tyr(Me)2)-1-Carbaoxytocin, (Butyryl1,Tyr(Me)2)-Oxytocin
BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2 TRIFLUOROACETATE SALT
2-Deamino-L-Abu(1)-O-methyl-L-Tyr-L-Ile-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Leu-Gly-NH2
BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDE BOND BETWEEN BUTYRYL-4-YL AND CYS)
Glycinamide, N-(4-mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-, cyclic (1→5)-thioether
N-(4-Mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamidecyclic (1-5)-thioether acetate
CarbetocinQ: What is Carbetocin Q: What is the CAS Number of Carbetocin Q: What is the storage condition of Carbetocin Q: What are the applications of Carbetocin
[EINECS(EC#)]

253-312-6
[Molecular Formula]

C45H69N11O12S
[MDL Number]

MFCD05664397
[MOL File]

37025-55-1.mol
[Molecular Weight]

988.17
Chemical PropertiesBack Directory
[Melting point ]

140 - 160°C
[alpha ]

D -69.0° (c = 0.25 in 1M acetic acid)
[Boiling point ]

1477.9±65.0 °C(Predicted)
[density ]

1.218±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

powder
[pka]

13.07±0.70(Predicted)
[color ]

white to beige
[Water Solubility ]

Soluble to 29.65 mg/ml in water
[Stability:]

Hygroscopic
[InChIKey]

NSTRIRCPWQHTIA-FOILTOEQNA-N
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H312+H332
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

Carbetocin is an alternative synthetic oxytocin-receptor agonist available in Canada, the United Kingdom, and other countries,but not the United States. A large multinational randomized noninferiority trial (N=29,645) found that carbetocin was noninferior to oxytocin for prevention of postpartum hemorrhage and need for additional uterotonic agents after vaginal delivery. Carbetocin has a longer duration of action than oxytocin, eliminating the need for prolonged infusion.
[Uses]

Carbetocin is an obstetric drug used to control postpartum hemorrhaging.
[Definition]

ChEBI: Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue o oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.
[Biochem/physiol Actions]

Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin.
[Side effects]

One of the most commonly reported side effects of Carbetocin is hypotension, or low blood pressure. Another frequently observed side effect is nausea, often accompanied by vomiting. It can also cause headache.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Carbetocin(37025-55-1)1HNMR
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