ChemicalBook--->CAS DataBase List--->3704-09-4

3704-09-4

3704-09-4 Structure

3704-09-4 Structure
IdentificationMore
[Name]

Mibolerone
[CAS]

3704-09-4
[Synonyms]

17BETA-HYDROXY-7ALPHA,17-DIMETHYLESTR-4-EN-3-ONE
17-HYDROXY-7,17-DIMETHYL-ESTR-4-EN-3-ONE
4-ESTREN-7-ALPHA, 17-ALPHA-DIMETHYL-17-BETA-OL-3-ONE
7a,17a-dimethyl-19-nortestosterone
MIBOLERONE
U-10997
17-beta-hydroxy-7-alpha,17-dimethyl-estr-4-en-3-on
17-hydroxy-7,17-dimethyl-,(7-alpha,17-beta)-estr-4-en-3-on
miboleron
Mebolone
(7a,17b)-17-Hydroxy-7,17-dimethylestr-4-en-3-one
Chequ
(7a,17)-17-Hydroxy-7,17-dimethylestr-4-en-3-one
Cheque
Cheque Drops
Matenon
[EINECS(EC#)]

223-046-5
[Molecular Formula]

C20H30O2
[MDL Number]

MFCD00221774
[Molecular Weight]

302.45
[MOL File]

3704-09-4.mol
Chemical PropertiesBack Directory
[Appearance]

White Crystalline Solid
[Melting point ]

168-171°C
[Boiling point ]

383.47°C (rough estimate)
[density ]

1.0434 (rough estimate)
[refractive index ]

1.4980 (estimate)
[storage temp. ]

Controlled Substance, -20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Very Slightly)
[form ]

Solid
[pka]

15.13±0.60(Predicted)
[color ]

White to Off-White
[Usage]

Synthetic anabolic steroid related to testosterone. Controlled substance (anabolic steroid)
[InChI]

InChI=1/C20H30O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11-12,15-18,22H,4-10H2,1-3H3/t12-,15+,16-,17+,18-,19+,20+/s3
[InChIKey]

PTQMMNYJKCSPET-ICZNVABVNA-N
[SMILES]

[C@@]12([C@]3([H])CC[C@@](O)(C)[C@@]3(C)CC[C@]1([H])[C@@]1([H])CCC(=O)C=C1C[C@H]2C)[H] |&1:0,1,5,8,12,14,23,r|
[CAS DataBase Reference]

3704-09-4(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H360
[Hazard Codes ]

T
[Risk Statements ]

60-63
[Safety Statements ]

36-45
[HS Code ]

2937290000
[Safety Profile]

Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard InformationBack Directory
[Chemical Properties]

White Crystalline Solid
[Uses]

Synthetic anabolic steroid related to testosterone. Controlled substance (anabolic steroid)
[Definition]

ChEBI: An androgen that is nalandrone carrying two methyl substituents at positions 7alpha and 17.
[Synthesis]

Under nitrogen atmosphere, 30.0 mL of a freshly prepared 2.2 mol / L ethyl ether methyl lithium THF solution was cooled in an ice bath and 4.00 g (21 mmol) of cuprous iodide was added with stirring, followed by the addition of 3.00 g (10.5 mmol) of 6 -deh
[Veterinary Drugs and Treatments]

Cheque? Drops was labeled as indicated “for estrous (heat) prevention in adult female dogs not intended primarily for breeding purposes.” In clinical trials it was 90% effective in suppressing estrus.
Although not approved, mibolerone at dosages of 50 micrograms per day will prevent estrus in the cat, but its use is generally not recommended because of the very narrow therapeutic index of the drug in this species (see the Adverse Effects and Overdosage sections for more information).
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