| Identification | More | [Name]
3,5-Difluoroaniline | [CAS]
372-39-4 | [Synonyms]
3,5-DIFLUOROANILINE
3,5-DIFLUOROBENZENAMINE
3,5-Difluoroaniline(AntibacterialAntiphlogistic,WeedKiller)(C6H5F2N)
3,5-Difluoroaniline,98%
3,5-Difluoroaniline 98%
3,5-DIFLUOROBENZENEAMINE
Benzenamine, 3,5-difluoro
3,5-Difluoronitroaniline
3,5-Difluorophenylamine | [EINECS(EC#)]
206-752-8 | [Molecular Formula]
C6H5F2N | [MDL Number]
MFCD00007763 | [Molecular Weight]
129.11 | [MOL File]
372-39-4.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellowish low melting solid | [Melting point ]
37-41 °C (lit.) | [Boiling point ]
80°C 20mm | [density ]
1,295 g/cm3 | [refractive index ]
1,512-1,514 | [Fp ]
167 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Low Melting Solid | [pka]
2.57±0.10(Predicted) | [color ]
White to yellow | [BRN ]
2802286 | [CAS DataBase Reference]
372-39-4(CAS DataBase Reference) | [EPA Substance Registry System]
372-39-4(EPA Substance) |
| Questions And Answer | Back Directory | [Synthesis]
Work on halogenated benzenes has also demonstrated the versatility of this technique and a variety of fluoro-chloro and -bromo benzenes may be de-brominated and de-chlorinated. Two patents describe removal of chlorine from 2,6-dichloro-3,5- difluoronitrobenzene giving 3,5-difluoroaniline.
|
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 1325 4.1/PG 2
| [WGK Germany ]
3
| [F ]
8-10-23 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214200 |
| Raw materials And Preparation Products | Back Directory | [Preparation Products]
2,4-dibromo-1,3,5-trifluorobenzene-->4-AMINO-2,6-DIFLUORO-BENZALDEHYDE-->2,4,6-Trifluorochlorobenzene-->2-AMINO-4,6-DIFLUOROBENZOIC ACID-->3,5-Difluoro-4-iodoaniline-->3,5-DIFLUOROBENZENESULFONAMIDE-->N-Methyl 3,5-difluoroaniline-->1,3,5-Trifluorobenzene-->N-(3,5-Difluorophenyl)-4-nitrobenzenesulfonaMide, 97%-->Benzenamine, 3,5-difluoro-N,N-dimethyl- (9CI)-->N-(3,5-Difluorophenyl)-4-fluorobenzaMide, 97%-->2-(3,5-Difluorophenoxy)acetic acid-->5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid ethyl ester |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellowish low melting solid | [Uses]
3,5-Difluoroaniline has been used in the preparation of 3,5-difluorodimethylaniline. | [General Description]
In vitro nephrotoxic effects of 3,5-difluoroaniline has been investigated in renal cortical slices obtained from the kidneys of untreated, male Fischer 344 rats. |
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