ChemicalBook--->CAS DataBase List--->376608-71-8

376608-71-8

376608-71-8 Structure

376608-71-8 Structure
IdentificationBack Directory
[Name]

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanamine(S)-(carboxylato(phenyl)methyl)holmium
[CAS]

376608-71-8
[Synonyms]

Ticagrelor Intermediate3
Ticagrelor InterMediate 4
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium
(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaMiniuM (2
(1R,2S)-2-(3,4-Difluorophenyl) cyclopropylamine D-Mandelate
trans-(1R,2S)-2-(2,3-difluorophenyl)cyclopropylaMine Mandelat
Trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropylamine mandelate
(1S,2R)-2-(3,4- difluorophenyl)cyclopropan-1-amine hydrochloride
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaMiniuM(2R)-hydroxy(phenyl)
(1R,2S)-2-(3,4-difluorophenyl)cyclopropanaMine (S)-2-hydroxy-2-phenylacetate
(1R,2S)-2-(3,4-dimethylphenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate
(1R,2S)-2-(3,4-difluorophenyl)cyclopropanaMine (R)-2-hydroxy-2-phenylacetate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaMine (2R)-Hydroxy(phenyl)ethanoate
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate
(1R,2S)-2-(3,4-Difluorophenyl) cyclopropanaminium (2R)-hydroxy(phenyl)ethanoat
(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine (R)-2-hydroxy-2-phenylacetate
(1S,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine (R)-2-hydroxy-2-phenylacetate
(1R,2S)-2-(3,4-difluorophenyl)cyclopropanaMine with (R)-(-)-Mandelic acid (1:1)
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetic acid
(1R,2S)-2-(3,4-difluorophenyl)cyclopropanaMine (R)-2-hydroxy-2-phenylacetate(1:1)
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanamine(S)-(carboxylato(phenyl)methyl)holmium
(αR)-α-Hydroxybenzeneacetic Acid coMpd. with (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaMine
Benzeneaceticacid,a-hydroxy-,(R)-(1R,2S)-coMpd.with2-(3,4-difluorophenyl)cyclopropanaMine(1:1)
(αR)-(1R,2S)-α-hydroxy-Benzeneacetic acid-coMpd.with 2-(3,4-difluorophenyl)cyclopropanaMine(1:1)
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
(alphaR)-alpha-Hydroxybenzeneacetic acid compd. with (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine
Benzeneacetic acid, α-hydroxy-, (αR)-(1R,2S)-coMpd. with 2-(3,4-difluorophenyl)cyclopropanaMine (1:1)
[EINECS(EC#)]

1308068-626-2
[Molecular Formula]

C17H17F2NO3
[MDL Number]

MFCD21362980
[MOL File]

376608-71-8.mol
[Molecular Weight]

321.319
Chemical PropertiesBack Directory
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
Hazard InformationBack Directory
[Chemical Properties]

White to off-white powder
[Uses]

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists for the prevention of thrombosis.
Safety DataBack Directory
[Safety Statements ]

24/25
[HS Code ]

29181990
Questions and Answers (Q&A)Back Directory
[Description]

(1R, 2R)-2-(3, 4-difluorophenyl) cyclopropanamine(S)-(carboxylato(phenyl)methyl) holmium is a useful pharmacological intermediate. It is utilized as an intermediate of trcagrelor, which is a platelet aggregation inhibitor used for prevention of thrombotic events occurring in people with acute coronary syndrome or myocardial infarction.
[References]

http://www.tradekorea.com/product/detail/P483269/Ticagrelor-intermediates---CAS-376608-71-8.html
https://en.wikipedia.org/wiki/Ticagrelor
Spectrum DetailBack Directory
[Spectrum Detail]

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate(376608-71-8)1HNMR
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