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379270-35-6

379270-35-6 Structure

379270-35-6 Structure
IdentificationBack Directory
[Name]

[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester
[CAS]

379270-35-6
[Synonyms]

TAF Impurity 3
Monophenylester
GS7340 impurity1
GS7340 intermediate 1
Tenofovir Impurity 30
Tenofovir alafenamide-4
Tenofovir Related Compound 2
Tenofovir Alafenamide Impurity 28
Tenofovir Alafenamide Impurity 18
Tenofovir Alafenamide Fumarate N-3
Tenofovir alafenamide Intermediate
Tenofovir Monophenyl Ester Impurity
Tenofovir alafenamide Intermediate 1
The intermediate of Tenofovir Alafenamide
9-[(R)-2- (phenylphosphonomethoxy) propyl]adenine (PPMPA)
Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methyleth...
(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-phenoxy-phosphinic acid
[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester
phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate
[2-(6-Amino-purin-9- yl)-1-methyl-ethoxy methyl]-phosphonic acid monophenyl ester
Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate
phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenylester
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenyl ester (9CI)
[EINECS(EC#)]

807-851-4
[Molecular Formula]

C15H18N5O4P
[MDL Number]

MFCD28386144
[MOL File]

379270-35-6.mol
[Molecular Weight]

363.31
Questions And AnswerBack Directory
[Appearance]

White powder
Chemical PropertiesBack Directory
[Melting point ]

237-239°C
[Boiling point ]

610.1±65.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[solubility ]

Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
[form ]

Solid
[pka]

2.09±0.10(Predicted)
[color ]

White to Off-White
[InChI]

InChI=1S/C15H18N5O4P/c1-11(7-20-9-19-13-14(16)17-8-18-15(13)20)23-10-25(21,22)24-12-5-3-2-4-6-12/h2-6,8-9,11H,7,10H2,1H3,(H,21,22)(H2,16,17,18)/t11-/m1/s1
[InChIKey]

ITAMCOCNZJPJDF-LLVKDONJSA-N
[SMILES]

C(P(=O)(O)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2
Safety DataBack Directory
[REACH Registrations]

Active
Hazard InformationBack Directory
[Uses]

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
[Application]

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
Spectrum DetailBack Directory
[Spectrum Detail]

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate(379270-35-6)1HNMR
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