| Identification | More | [Name]
3,4-Diethoxyphenylacetic acid | [CAS]
38464-04-9 | [Synonyms]
2-(3,4-DIETHOXYPHENYL)ACETIC ACID
3,4-DIETHOXYPHENYLACETIC ACID
3,4-DIETHYLOXY PHENYLACETIC ACID
AKOS B006522
ART-CHEM-BB B006522
BENZENEACETIC ACID, 3,4-DIETHOXY-
CHEMBRDG-BB 3006522
RARECHEM AL BO 0610
VITAS-BB TBB000357
3,4-Diethoxyphenylphenylaceticacid
3,4-diethoxybenzeneacetic acid
3,4-Diethyloxy
2-(3,4-BIS(HYDROXYMETHYL)PHENYL)ACETIC ACID | [EINECS(EC#)]
253-957-3 | [Molecular Formula]
C12H16O4 | [MDL Number]
MFCD00040785 | [Molecular Weight]
224.25 | [MOL File]
38464-04-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
77-79°C | [Boiling point ]
357.2±27.0 °C(Predicted) | [density ]
1.133±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
4.36±0.10(Predicted) | [color ]
White to Orange to Green | [InChI]
InChI=1S/C12H16O4/c1-3-15-10-6-5-9(8-12(13)14)7-11(10)16-4-2/h5-7H,3-4,8H2,1-2H3,(H,13,14) | [InChIKey]
FIKUHWAANCXBGJ-UHFFFAOYSA-N | [SMILES]
C1(CC(O)=O)=CC=C(OCC)C(OCC)=C1 | [CAS DataBase Reference]
38464-04-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
3,4-Diethoxyphenylacetic acid is used as an intermediate in the drug drotaverine (trataverine). | [Synthesis]
0.8 g of 3,4-dihydroxy-phenylacetic acid and 6.9 g of barium hydroxide octahydrate are dissolved in 50 ml of water and at ambient temperature 2.9 ml of diethylsulphate are added dropwise.. The solution is stirred for 2 hours at ambient temperature and for 2 hours at 40° C. After this time, the solution is acidified with saturated potassium hydrogen sulphate solution, mixed with ethyl acetate and the suspension is filtered through Celite. The phases are separated, and the ethyl acetate phase is dried over sodium sulphate and concentrated by evaporation. The residue obtained from 3,4-Diethoxyphenylacetic acid is purified through a silica gel column with toluene/ethyl acetate/ethanol (4:2:1) as eluant.
|
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|