ChemicalBook--->CAS DataBase List--->3940-27-0

3940-27-0

3940-27-0 Structure

3940-27-0 Structure
IdentificationBack Directory
[Name]

ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE
[CAS]

3940-27-0
[Synonyms]

NSC 29417
H-DL-Ser-OEt·HCl
H-DL-Serine ethyl ester HCl
DL-Serine Ethyl Ester Hydrochoride
DL-SERINE ETHYL ESTER HYDROCHLORIDE
ethyl2-amino-3-hydroxypropanoateHCl
H-DL-Serine ethyl ester hydrochloride
ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE
Ethyl 2-amino-3-hydroxypropanoate hydrochloride 98%
(D,L)-ethyl 2-amino-3-hydroxypropanoate hydrochloride
ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE USP/EP/BP
[Molecular Formula]

C5H12ClNO3
[MDL Number]

MFCD00067544
[MOL File]

3940-27-0.mol
[Molecular Weight]

169.61
Chemical PropertiesBack Directory
[Melting point ]

98-100°C
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[Appearance]

White to off-white Solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H335-H302+H312+H332-H315
[Precautionary statements ]

P280-P301+P312-P362+P364
[Risk Statements ]

22-36/37/38
[Safety Statements ]

22-26-36/37/39
[HS Code ]

2916399090
Hazard InformationBack Directory
[Uses]

H-DL-Serine ethyl ester HCl
[Synthesis]

Ethanol

64-17-5

L-Serine

56-45-1

ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE

3940-27-0

1. 5.4 mL of thionyl chloride (about two drops) was slowly added dropwise to a 100 mL three-necked flask containing 40 mL of ethanol under an ice-water bath and mechanical stirring, and stirring was continued for 1 hr after completion of the dropwise addition. 2. 6.00 g (57 mmol) of L-serine was added to the above reaction system and the reaction was heated to reflux for 10 hours. 3. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give 9.05 g of the white solid product L-serine ethyl ester hydrochloride (III) in 93.4% yield.

[References]

[1] Patent: CN105777611, 2016, A. Location in patent: Paragraph 0052; 0053
Spectrum DetailBack Directory
[Spectrum Detail]

ETHYL 2-AMINO-3-HYDROXYPROPANOATE HYDROCHLORIDE(3940-27-0)1HNMR
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