| Identification | Back Directory | [Name]
4-(4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl)benzene-1,3-diol | [CAS]
394237-61-7 | [Synonyms]
M77976
4-(4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl)benzene-1,3-diol
1,3-Benzenediol, 4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]- | [Molecular Formula]
C17H16N2O3 | [MDL Number]
MFCD01995504 | [MOL File]
394237-61-7.mol | [Molecular Weight]
296.32 |
| Chemical Properties | Back Directory | [Boiling point ]
508.1±50.0 °C(Predicted) | [density ]
1.295±0.06 g/cm3(Predicted) | [solubility ]
DMSO: 250 mg/mL (843.68 mM) | [form ]
Solid | [pka]
8.55±0.35(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
M77976 is a specific ATP-competitive inhibitor of PDK4 (pyruvate dehydrogenase kinase isoforms 4), with an IC50 of 648 μM. M77976 is potential for the research of obesity and diabetes[1]. | [References]
[1] Kukimoto-Niino M, et al. Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4. Acta Crystallogr D Biol Crystallogr. 2011 Sep;67(Pt 9):763-73. DOI:10.1107/S090744491102405X |
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cjbscvictory
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13348960310 13348960310; |
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https://www.weikeqi-biotech.com/ |
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Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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