| Identification | Back Directory | [Name]
2,2-DIFLUOROACETOPHENONE | [CAS]
395-01-7 | [Synonyms]
A,A-DIFLUOROACETOPHENONE
2,2-DIFLUOROACETOPHENONE
2,2-Difluoroacetophenone97%
2,2-Difluoroacetophenone 97%
2,2-Difluoroacetophenone,95%
2,2-DIFLUORO-1-PHENYLETHANONE
2,2-Difluoro-1-phenylethan-1-one
ALPHA,ALPHA-DIFLUOROACETOPHENONE
Ethanone, 2,2-difluoro-1-phenyl-
Ethanone, 2,2-difluoro-1-phenyl- (9CI)
2,2-Difluoro-1-phenylethan-1-one, 2,2-Difluoro-1-phenyl-1-oxoethane | [Molecular Formula]
C8H6F2O | [MDL Number]
MFCD06246879 | [MOL File]
395-01-7.mol | [Molecular Weight]
156.13 |
| Chemical Properties | Back Directory | [Melting point ]
48-50°C | [Boiling point ]
53-54°C/12mm | [density ]
1.180±0.06 g/mL | [refractive index ]
1.4955 | [Fp ]
53-54°C/12mm | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
liquid | [Water Solubility ]
Immiscible with water. | [CAS DataBase Reference]
395-01-7 |
| Hazard Information | Back Directory | [Uses]
2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee. | [Synthesis Reference(s)]
Tetrahedron, 52, p. 15, 1996 DOI: 10.1016/0040-4020(95)00884-B |
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