ChemicalBook--->CAS DataBase List--->434-45-7

434-45-7

434-45-7 Structure

434-45-7 Structure
IdentificationMore
[Name]

Trifluoroacetophenone
[CAS]

434-45-7
[Synonyms]

2,2,2-TRIFLUORO-1-PHENYLETHAN-1-ONE
2,2,2-TRIFLUORO-1-PHENYLETHANONE
2,2,2-TRIFLUOROACETOPHENONE
A,A,A-TRIFLUOROACETOPHENONE
ALPHA,ALPHA,ALPHA-TRIFLUOROACETOPHENONE
PHENYL TRIFLUOROMETHYL KETONE
TRIFLUOROACETOPHENONE
TRIFLUOROACETYLBENZENE
1,1,1-Trifluoroacetophenone
2,2,2-Trifluoro-1-phenylethanoate
2,2,2-trifluoro-1-phenyl-ethanon
Acetophenone, 2,2,2-trifluoro-
Ethanone, 1,1,1-trifluoro,2-phenyl-
omega,omega,omega-Trifluoroacetophenone
Trifluoromethyl phenyl ketone
Phenyl trifluoromethyl ketone~2,2,2-Trifluoroacetophenone
alpha,alpha,alpha-Trifluoroacethophenone
Ethanone, 2,2,2-trifluoro-1-phenyl-(9CI)
Ethanone, 2,2,2-trifluoro-1-phenyl-
2,2,2-Trifluoroacetophenone 99%
[EINECS(EC#)]

207-103-1
[Molecular Formula]

C8H5F3O
[MDL Number]

MFCD00000420
[Molecular Weight]

174.12
[MOL File]

434-45-7.mol
Chemical PropertiesBack Directory
[Appearance]

CLEAR COLORLESS TO YELLOW LIQUID
[Melting point ]

-40 °C
[Boiling point ]

165-166 °C (lit.) 46-48 °C/14 mmHg (lit.)
[density ]

1.24 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.458(lit.)
[Fp ]

107 °F
[storage temp. ]

Flammables area
[solubility ]

Chloroform, Ethyl Acetate
[form ]

Liquid
[color ]

Clear colorless to yellow
[Specific Gravity]

1.240
[Water Solubility ]

PRACTICALLY INSOLUBLE
[BRN ]

1866286
[InChI]

1S/C8H5F3O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H
[InChIKey]

KZJRKRQSDZGHEC-UHFFFAOYSA-N
[SMILES]

FC(F)(F)C(=O)c1ccccc1
[CAS DataBase Reference]

434-45-7(CAS DataBase Reference)
[NIST Chemistry Reference]

Ethanone, 2,2,2-trifluoro-1-phenyl-(434-45-7)
[EPA Substance Registry System]

Ethanone, 2,2,2-trifluoro-1-phenyl- (434-45-7)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Warning
[Hazard statements ]

H226-H315-H319-H335
[Precautionary statements ]

P210-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi,F
[Risk Statements ]

R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking .
[RIDADR ]

UN 1224 3/PG 3
[WGK Germany ]

3
[Hazard Note ]

Corrosive/Lachrymatory
[TSCA ]

T
[HazardClass ]

3
[PackingGroup ]

III
[HS Code ]

29147090
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2,2,2-Trifluoroacetophenone(434-45-7).msds
Hazard InformationBack Directory
[Chemical Properties]

CLEAR COLORLESS TO YELLOW LIQUID
[Uses]

2,2,2-Trifluoroacetophenone is a fluorinated acetophenone with inhibitory activity of acetylcholinesterase. 2,2,2-Trifluoroacetophenone was shown to have neuroprotective activity by inhibiting apoptos is in cerebellar granule neurons.
[General Description]

2,2,2-Trifluoroacetophenone is the starting material for the synthesis of f 3-trifluoromethyl-3-phenyldiazirine. It undergoes asymmetric reduction with optically active Grignard reagent to form 2,2,2-trifluoro-1-phenylethanol. It undergoes condensation with biphenyl, terphenyl, a mixture of biphenyl with terphenyl, phenyl ether and diphenoxybenzophenone to form new aromatic 3F polymers.
[Synthesis]

2,2,2-Trifluoroacetophenone is commonly synthesized by the following methods: (1) Trifluoroacetic acid is directly synthesized in one step by reacting directly with the Grignard reagent of bromobenzene. The yield is about 60%. The advantages of this metho
Spectrum DetailBack Directory
[Spectrum Detail]

Trifluoroacetophenone(434-45-7)MS
Trifluoroacetophenone(434-45-7)1HNMR
Trifluoroacetophenone(434-45-7)IR1
Trifluoroacetophenone(434-45-7)IR2
Trifluoroacetophenone(434-45-7)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

alpha,alpha,alpha-Trifluoroacetophenone, 99%(434-45-7)
[Alfa Aesar]

2,2,2-Trifluoroacetophenone, 98%(434-45-7)
[Sigma Aldrich]

434-45-7(sigmaaldrich)
[TCI AMERICA]

2,2,2-Trifluoroacetophenone,>98.0%(GC)(434-45-7)
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