ChemicalBook--->CAS DataBase List--->4102-53-8

4102-53-8

4102-53-8 Structure

4102-53-8 Structure
IdentificationMore
[Name]

4-Iodo-2,6-dimethylaniline
[CAS]

4102-53-8
[Synonyms]

4-IODO-2,6-DIMETHYLANILINE
4-Iodo-2,6-dimethylaniline( 4-Iodo-2,6-xylidine)
4-IODO-2,6-DIMETHYLANILINE 99%
[EINECS(EC#)]

609-884-8
[Molecular Formula]

C8H10IN
[MDL Number]

MFCD08061611
[Molecular Weight]

247.08
[MOL File]

4102-53-8.mol
Chemical PropertiesBack Directory
[Melting point ]

52 °C
[Boiling point ]

120 °C(Press: 0.998 Torr)
[density ]

1.688±0.06 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[pka]

3.51±0.10(Predicted)
[Appearance]

Brown to dark brown Solid
[CAS DataBase Reference]

4102-53-8(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H332-H335-H312-H315-H302
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

4-Iodo-2,6-dimethylaniline is an intermediate in organic synthesis and pharmaceutical intermediate, which can be used in laboratory research and pharmaceutical synthesis process.
[Synthesis]

4-Iodo-2,6-dimethylaniline was prepared by reacting iodine,ethyl acetate and acetic acid in prestence of SPC and then heated with 2,6-dimethylaniline at 45-50℃ for 1 h.

Synthetic route of 4-iodo-2,6-dimethylaniline

[References]

[1] Journal of the American Chemical Society, 2013, vol. 135, # 5, p. 1692 - 1695
[2] Tetrahedron, 2005, vol. 61, # 49, p. 11657 - 11663
[3] Inorganic Chemistry, 2014, vol. 53, # 13, p. 6837 - 6843
[4] Bulletin of the Chemical Society of Japan, 1988, vol. 61, # 2, p. 600 - 602
[5] Organic Letters, 2011, vol. 13, # 11, p. 2936 - 2939
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