ChemicalBook--->CAS DataBase List--->4143-74-2

4143-74-2

4143-74-2 Structure

4143-74-2 Structure
IdentificationBack Directory
[Name]

4'-METHOXYFLAVONE
[CAS]

4143-74-2
[Synonyms]

4'-METHOXYFLAVONE
METHOXYFLAVONE, 4'-
2-(4-methoxyphenyl)chromone
2-(4-methoxyphenyl)-4-benzopyrone
2-(4-Methoxy-phenyl)-chromen-4-one
4' METHOXYFLAVONE,4'METHOXYFLAVONE
2-(4-methoxyphenyl)-4h-1-benzopyran-4-on
2-(4-Methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,2-(4-methoxyphenyl)-
[EINECS(EC#)]

223-968-8
[Molecular Formula]

C16H12O3
[MDL Number]

MFCD00016934
[MOL File]

4143-74-2.mol
[Molecular Weight]

252.26
Chemical PropertiesBack Directory
[Melting point ]

157-158°C
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble5mg/mL, clear (warmed)
[form ]

lyophilized powder
[color ]

white
[LogP]

3.820 (est)
[CAS DataBase Reference]

4143-74-2
[EPA Substance Registry System]

4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)- (4143-74-2)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[TSCA ]

TSCA listed
[HS Code ]

2932.99.9090
Hazard InformationBack Directory
[Uses]

4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research[1].
[Definition]

ChEBI:2-(4-methoxyphenyl)-1-benzopyran-4-one is a member of flavonoids and an ether.
[Biological Activity]

4-methoxyflavone is a neuroprotective agent th at inhibits the accumulation of poly (ADP-ribose) and neuronal cell death following chemically-induced DNA damage or NMDA excitation.
[References]

[1] Walle U K, et al. Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones[J]. Drug Metabolism and Disposition, 2007, 35(11): 1985-1989. DOI:10.1124/dmd.107.016782
Spectrum DetailBack Directory
[Spectrum Detail]

4'-METHOXYFLAVONE(4143-74-2)1HNMR
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