ChemicalBook--->CAS DataBase List--->4248-64-0

4248-64-0

4248-64-0 Structure

4248-64-0 Structure
IdentificationBack Directory
[Name]

Oxytocin (free acid)
[CAS]

4248-64-0
[Synonyms]

Oxytocic Acid
Oxytocinoic acid
9-Deamidooxytocin
Oxytocin Impurity 9
Oxytocin, 9-glycine-
Oxytocin Impurity 5 TrifluoroacetateOxytocin Impurity 9 TrifluoroacetateOxytocin Impurity 10
2-((S)-2-((S)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-((S)-sec-butyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-4-methylpentanamido)acetic acid
[Molecular Formula]

C43H65N11O13S2
[MOL File]

4248-64-0.mol
[Molecular Weight]

1008.18
Chemical PropertiesBack Directory
[Boiling point ]

1522.6±65.0 °C(Predicted)
[density ]

1.281±0.06 g/cm3(Predicted)
[pka]

3.35±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Oxytocin free acid (9-Deamidooxytocin) is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior[1][2].
[References]

[1] Ferrier BM, et al. 9-Deamidooxytocin, an analog of the hormone containing a glycine residue in place of the glycinamide residue. J Med Chem. 1966;9(1):55-57. DOI:10.1021/jm00319a014
[2] Carter CS, Kenkel WM, MacLean EL, et al. Is Oxytocin "Nature's Medicine"?. Pharmacol Rev. 2020;72(4):829-861. DOI:10.1124/pr.120.019398
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