| Identification | Back Directory | [Name]
N-[4-Methyl-9-(1-methylethyl)-9H-carbazol-3-yl]-4-morpholinecarboxamide | [CAS]
439861-56-0 | [Synonyms]
NPY 5RA972 NPY 5RA972,NPY 5RA-972 N-(9-Isopropyl-4-methyl-9H-carbazol-3-yl)morpholine-4-carboxamide N-[4-Methyl-9-(1-methylethyl)-9H-carbazol-3-yl]-4-morpholinecarboxamide 4-Morpholinecarboxamide, N-[4-methyl-9-(1-methylethyl)-9H-carbazol-3-yl]- | [Molecular Formula]
C21H25N3O2 | [MDL Number]
MFCD16618400 | [MOL File]
439861-56-0.mol | [Molecular Weight]
351.44 |
| Hazard Information | Back Directory | [Uses]
NPY 5RA972 is a potent antagonist of the neuropeptide Y5 receptor. | [in vivo]
NPY5RA-972(p.o., 10.5 mg/kg) has a Tmax value of 1 hour in rats, a Cmax of 35 μM, a half-life of 6.4 hours, and a total plasma concentration of greater than 3 μM/h even 24 hours after administration[1].
NPY5RA-972 (p.o., 1-10 mg/kg) inhibits food intake elicited by a selective NPY Y5 receptor agonist, but has no effect on food intake or body weight in freely-fed Wistar rats or diet-obese rats Influence[1].
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