| Identification | Back Directory | [Name]
5,7,8-TRIHYDROXYFLAVONE | [CAS]
4443-09-8 | [Synonyms]
NORWOGONIN
Dimethylhanxanthin
5,7,8-HYDROXYFLAVONE
5,7,8-TRIHYDROXYFLAVONE
5,7,8-trihydroxy-flavon
TRIHYDROXYFLAVONE, 5,7,8-
TRIHYDROXYFLAVONE, 5,7,8-(RG)
2-phenyl-5,7,8-trihydroxy-4h-1-benzopyran-4-on
2-phenyl-5,7,8-trihydroxy-4h-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7,8-trihydroxy-2-phenyl- | [Molecular Formula]
C15H10O5 | [MDL Number]
MFCD00016946 | [MOL File]
4443-09-8.mol | [Molecular Weight]
270.24 |
| Chemical Properties | Back Directory | [Melting point ]
227-228 °C | [Boiling point ]
528.4±50.0 °C(Predicted) | [density ]
1.548±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
6.66±0.40(Predicted) | [color ]
Yellow | [InChI]
InChI=1S/C15H10O5/c16-9-6-11(18)14(19)15-13(9)10(17)7-12(20-15)8-4-2-1-3-5-8/h1-7,16,18-19H | [InChIKey]
ZFKKRRMUPBBYRS-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=CC=C2)OC2=C(O)C(O)=CC(O)=C2C(=O)C=1 | [LogP]
1.970 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the tuberous root of Scutellaria baicalensis Georgi. | [Uses]
Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml[1] | [Definition]
ChEBI: A trihydroxyflavone with the hydroxy groups at positions C-5, -7 and -8. | [target]
VHR | [References]
[1] Choi HJ, et al. Inhibitory Effects of Norwogonin, Oroxylin A, and Mosloflavone on Enterovirus 71. Biomol Ther (Seoul). 2016 Sep 1;24(5):552-8. DOI:10.4062/biomolther.2015.200 |
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