ChemicalBook--->CAS DataBase List--->446-35-5

446-35-5

446-35-5 Structure

446-35-5 Structure
IdentificationMore
[Name]

2,4-Difluoronitrobenzene
[CAS]

446-35-5
[Synonyms]

1,3-difluoro-4-nitrobenzene
2,4-DIFLUORO-1-NITROBENZENE
2,4-DIFLUORONITROBENZENE
1-Nitro-2,4-difluorobenzene
2,4-difluoro-1-nitro-benzen
2,4-Difluronitrobenzene
Benzene, 2,4-difluoro-1-nitro-
2,4-DIFLUORO NITROBENZEN
2,4-Difluoronitribenzene
Benzene, 2,4-difluoro-1-nitro-(6CI,7CI,8CI,9CI)
3,5-diflurobenzonitrile
2,4-Difluoronitrobenzene99%
2,4-DIFLUORONITROBENZENE =99%(HPLC)
[EINECS(EC#)]

207-167-0
[Molecular Formula]

C6H3F2NO2
[MDL Number]

MFCD00007050
[Molecular Weight]

159.09
[MOL File]

446-35-5.mol
Chemical PropertiesBack Directory
[Appearance]

yellow liquid
[Melting point ]

9-10 °C (lit.)
[Boiling point ]

203-204 °C (lit.)
[density ]

1.451 g/mL at 25 °C(lit.)
[vapor density ]

>1 (vs air)
[refractive index ]

n20/D 1.511(lit.)
[Fp ]

195 °F
[storage temp. ]

Sealed in dry,Room Temperature
[form ]

clear liquid
[color ]

Light yellow to Brown
[Specific Gravity]

1.45
[Stability:]

Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
[Water Solubility ]

Insoluble in water.
[BRN ]

2048034
[InChIKey]

RJXOVESYJFXCGI-UHFFFAOYSA-N
[CAS DataBase Reference]

446-35-5(CAS DataBase Reference)
[NIST Chemistry Reference]

2,4-Difluoronitrobenzene(446-35-5)
[EPA Substance Registry System]

446-35-5(EPA Substance)
Questions And AnswerBack Directory
[Synthesis]

KF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown recently to work in dimethylformamide (DMF), important owing to the low cost16 of DMF.Synthesis of 2,4-Difluoronitrobenzene
Safety DataBack Directory
[Hazard Codes ]

T,Xi,Xn
[Risk Statements ]

R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
[RIDADR ]

UN 2810 6.1/PG 1
[WGK Germany ]

3
[RTECS ]

CZ5730000
[Hazard Note ]

Irritant
[TSCA ]

T
[HazardClass ]

6.1
[PackingGroup ]

III
[HS Code ]

29049090
Raw materials And Preparation ProductsBack Directory
[Raw materials]

1,3-Difluorobenzene-->tetrakis(N,N-DIethylaMino)phosphorus broMide-->Tetrabutylphosphonium bromide-->2,4-Dichloronitrobenzene
[Preparation Products]

2,4-Difluoroaniline-->5-Fluoro-2-oxindole-->3-Fluoro-4-nitroanisole-->3-Fluoro-4-nitroaniline-->1,5-Difluoro-2,4-dinitrobenzene-->2,6-Difluoronitrobenzene-->2-Chloro-4-fluoronitrobenzene-->1-Fluoro-3-nitrobenzene
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2,4-Difluoronitrobenzene(446-35-5).msds
Hazard InformationBack Directory
[Chemical Properties]

yellow liquid
[Uses]

2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction; (±)-horsfiline; resin-bound 2-arylaminobenzimidazoles.
[General Description]

Nucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module.
Spectrum DetailBack Directory
[Spectrum Detail]

2,4-Difluoronitrobenzene(446-35-5)MS
2,4-Difluoronitrobenzene(446-35-5)1HNMR
2,4-Difluoronitrobenzene(446-35-5)13CNMR
2,4-Difluoronitrobenzene(446-35-5)IR1
2,4-Difluoronitrobenzene(446-35-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2,4-Difluoronitrobenzene, 99%(446-35-5)
[Alfa Aesar]

2,4-Difluoro-1-nitrobenzene, 98%(446-35-5)
[Sigma Aldrich]

446-35-5(sigmaaldrich)
[TCI AMERICA]

2,4-Difluoronitrobenzene,>98.0%(GC)(446-35-5)
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