| Identification | More | [Name]
4-FLUOROPHENYL METHYL SULFONE | [CAS]
455-15-2 | [Synonyms]
1-FLUORO-4-(METHYLSULFONYL)BENZENE
4-FLUOROPHENYL METHYL SULFONE
4-FLUOROPHENYL METHYL SULPHONE
Sulfone, p-fluorophenyl methyl
1-fluoro-4-(methylsulphonyl)benzene
4-Fluorophenylmethylsulfone,97%
4-Fluorobenzenesulfinic Acid Methyl Este
4-Fluorophenyl
4-Fluorophenyl methyl sulphone 98%
4-Fluorophenylmethylsulphone98%
Benzene,1-fluoro-4-(methylsulfonyl)-
4-Fluorobenzenesulfinic Acid Methyl Ester
Methyl 4-fluorophenyl sulfone
Methyl(4-fluorophenyl) sulfone
p-Fluorophenyl(methyl) sulfone | [EINECS(EC#)]
207-237-0 | [Molecular Formula]
C7H7FO2S | [MDL Number]
MFCD00039753 | [Molecular Weight]
174.19 | [MOL File]
455-15-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
78-81 °C (lit.) | [Boiling point ]
95-97°C 7mm | [density ]
1.2768 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform, Dichloromethane, Dimethyl Sulfoxide, Methanol | [form ]
Adhering Crystalline Powder | [color ]
Almost white | [BRN ]
2045674 | [InChI]
InChI=1S/C7H7FO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,1H3 | [InChIKey]
DPJHZJGAGIWXTD-UHFFFAOYSA-N | [SMILES]
C1(F)=CC=C(S(C)(=O)=O)C=C1 | [CAS DataBase Reference]
455-15-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29309090 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
4-Fluorophenyl methyl sulfone was used in the preparation of 4-(4′-trifluoromethoxyphenoxy)phenyl methyl sulfone. | [Uses]
4-Fluorophenyl methyl sulfone is used for preparation of substituted indazole amides as glucokinase activators.
| [Synthesis]
A 500 mL flask was charged with 25.2 g of sodium sulfite, 100 mL of water, and 16.8
g of sodium bicarbonate. Heat to reflux and after all the solids are dissolved, add 21.0 g of 4-fluorobenzenesulfonyl chloride in batches and continue to heat to re |
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