| Identification | More | [Name]
3-Fluoroanisole | [CAS]
456-49-5 | [Synonyms]
M-FLUOROANISOLE
M-FLUORO METHOXYBENZENE
1-Fluoro-3-methoxybenzene
1-fluoro-3-methoxy-benzene
Benzene, 1-fluoro-3-methoxy-
3-Fluoroanisole,99%
3-Fluoroanisole 99%
m-Fluorophenyl methyl ether
3-Fluorophenyl(methyl) ether | [EINECS(EC#)]
207-267-4 | [Molecular Formula]
C7H7FO | [MDL Number]
MFCD00000335 | [Molecular Weight]
126.13 | [MOL File]
456-49-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to straw yellow liquid | [Melting point ]
-35°C | [Boiling point ]
158 °C/743 mmHg (lit.) | [density ]
1.104 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.488(lit.)
| [Fp ]
111 °F
| [storage temp. ]
Flammables area | [solubility ]
Chloroform, Methanol | [form ]
Oil | [color ]
Colourless | [Specific Gravity]
1.104 | [BRN ]
1858895 | [InChI]
InChI=1S/C7H7FO/c1-9-7-4-2-3-6(8)5-7/h2-5H,1H3 | [InChIKey]
MFJNOXOAIFNSBX-UHFFFAOYSA-N | [SMILES]
C1(F)=CC=CC(OC)=C1 | [CAS DataBase Reference]
456-49-5(CAS DataBase Reference) | [NIST Chemistry Reference]
m-Fluoroanisole(456-49-5) |
| Questions And Answer | Back Directory | [Preparation]
Methanol (3.2 mL, 79 mmol) was slowly added to a solution of KOtBu (7.4 g, 66 mmol) and dimethylformamide (15 mL), followed by the addition of 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (6 mL). The solution was heated at 80°C for 30 minutes. 1,3-Difluorobenzene (2.6 mL, 26 mmol) was added to the mixture. The solution was heated again at 80°C for 3.5 hours. The reaction mixture was cooled to room temperature. The reaction mixture was washed with water and 10% brine (2 x). The reaction mixture was dried. The reaction mixture was concentrated. The obtained 3-Fluoroanisole was purified by rapid chromatography (1% EtOAc in hexane). |
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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