| Identification | Back Directory | [Name]
4-HYDROXY-3-METHOXYCINNAMALDEHYDE | [CAS]
458-36-6 | [Synonyms]
AT-51107
CONIFERALDEHYDE
p-Coniferaldehyde
coniferylaldehydel
CONIFERYL ALDEHYDE
Eugenol EP Impurity K
Ferulic Acid Impurity 3
3-(4-Hydroxy-3-methoxyphenyl)
4-Hydroxy-3-methoxyzimtaldehyde
4-HYDROXY-3-METHOXYCINNAMALDEHYDE
4'-hydroxy-3'-methoxyciаnaldehyde
4-HYDROXY-3-METHOXYCINNAMALDEHDYE
2-Methoxy-4-(3-oxo-1-propenyl)phenol
2-Methoxy-4-(3-oxopropene-1-yl)phenol
3-(3-Methoxy-4-hydroxyphenyl)propenal
4-Hydroxy-3-MethoxycinnaMaldehyde 98%
3-(4-Hydroxy-3-methoxyphenyl)-2-propenal
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-
3-(4-Hydroxy-3-Methoxyphenyl)acrylaldehyde
Eugenol Impurity 11（Eugenol EP Impurity K）
4-Hydroxy-3-MethoxycinnaMaldehyde USP/EP/BP
(E)-3-(4-hydroxy-3-Methoxyphenyl)acrylaldehyde
4-Hydroxy-3-methoxycinnamaldehyde, 98%, from Balanophora involucrata Hook.f.
4-Hydroxy-3-methoxycinnamaldehyde
DISCONTINUED PLEASE SEE H973078 (E-ISOMER) | [EINECS(EC#)]
207-278-4 | [Molecular Formula]
C10H10O3 | [MDL Number]
MFCD00075811 | [MOL File]
458-36-6.mol | [Molecular Weight]
178.18 |
| Chemical Properties | Back Directory | [Melting point ]
80-82 °C(lit.)
| [Boiling point ]
175 °C5 mm Hg(lit.)
| [density ]
1.1562 g/cm3 (101.5 ºC) | [refractive index ]
1.65635 | [Fp ]
175° | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.65±0.31(Predicted) | [color ]
Brown | [Odor]
at 50.00 % in dipropylene glycol. sweet graham cracker cookie bread crust bread baked toasted grain barley roasted barley vanilla custard dairy | [Odor Type]
bready | [Stability:]
Air Sensitive | [InChI]
InChI=1S/C10H10O3/c1-13-10-7-8(3-2-6-11)4-5-9(10)12/h2-7,12H,1H3 | [InChIKey]
DKZBBWMURDFHNE-UHFFFAOYSA-N | [SMILES]
C(=O)C=CC1=CC=C(O)C(OC)=C1 | [LogP]
1.160 | [EPA Substance Registry System]
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- (458-36-6) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Abies odorifera; Acer saccharinum, Juglans cinerea, Quercus sp., and Sequoia sp. | [Uses]
4-Hydroxy-3-methoxycinnamaldehyde is suitable for use in a study to investigate the antioxidant and antiradical activities of ferulates using a β-carotene-linoleate model system and a DPPH radical scavenging assay, respectively. | [Definition]
ChEBI: A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. | [General Description]
4-Hydroxy-3-methoxycinnamaldehyde is an isoflavonoid. It has been isolated from the insecticidally active hot dichloromethane extract of heartwood of Gliricidia sepium, seed kernels of Melia azedarach L and barks of Cinnamomum cebuense. | [in vivo]
Coniferaldehyde (0.05 mmol kg/day; i.p; for 6 weeks) activates the Nrf2 signaling pathway in primary chondrocytes and articular cartilage from the knee joints. And Coniferaldehyde alleviates cartilage destruction in OA mice[2]. | Animal Model: | B6 male mice (26 g; 8-10 weeks old), surgical-induced osteoarthritis (OA)[2] | | Dosage: | 0.05 mmol kg/day (approx. 8.9 mg/kg) | | Administration: | i.p; for 6 weeks | | Result: | Evidently alleviated the medial meniscus cartilage damage in mice subjected to the destabilization. |
| [storage]
4°C, protect from light |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|