ChemicalBook--->CAS DataBase List--->465-16-7

465-16-7

465-16-7 Structure

465-16-7 Structure
IdentificationBack Directory
[Name]

OLEANDRIN
[CAS]

465-16-7
[Synonyms]

neriol
neriolin
Folineri
corrigen
folinevin
FOLINERIN
OLEANDRIN
foliandrin
neriostene
oleandrina
Oleandrine
Aids161444
Aids-161444
OLEANDRIN(P)
OLEANDRIN(PLEASE CALL)(RG)
Oleandrigenin oleandroside
14-hydroxycard-20-(22)-enolide
(3beta,5beta,16beta)-hexopyranosyl)oxy)-14-hydroxy
(3-beta,5-beta,16-beta)-hexopyranosyl)oxy)-14-hydroxy
16-(acetyloxy)-3-((2,6-dideoxy-3-o-methyl-alpha-l-arabino-card-20(22)-enolid
6-dideoxy-3-o-methyl-l-arabino-hexopyranosyl)oxy]-16beta-(acetyloxy)-3beta-[(
16beta-acetoxy-3beta-(2,6-dideoxy-3-O-methyl-L-arabino-hexopyranosyloxy)-14-hydroxycard-20(22)-enolide
16-beta-acetoxy-3-beta-(2,6-dideoxy-3-O-methyl-L-arabino-hexopyranosyloxy)-14-hydroxycard-20(22)-enolide
5β,20(22)-Cardenolide-3β,14,16β-triol-3-([2,6-dideoxy-3-O-methyl-α-L-arabinohexopyranosyl]oxy) 16-acetate
(3,5,16)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
(3β,5β,16β)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-Methyl-α-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
(3b,5b,16b)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
(3beta,5beta,16beta)-16-(Acetyloxy)-3-[(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
[EINECS(EC#)]

207-361-5
[Molecular Formula]

C32H48O9
[MDL Number]

MFCD00079204
[MOL File]

465-16-7.mol
[Molecular Weight]

576.72
Chemical PropertiesBack Directory
[Appearance]

White to Off-White Solid
[Melting point ]

250°C
[alpha ]

D25 -48.0° (c = 1.3 in methanol)
[Boiling point ]

557.17°C (rough estimate)
[density ]

1.26
[refractive index ]

1.5000 (estimate)
[storage temp. ]

-20°C Freezer
[solubility ]

DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
[form ]

A solid
[pka]

13.55±0.70(Predicted)
[color ]

Crystals from dil methanol
[Major Application]

food and beverages
[InChIKey]

JLPDBLFIVFSOCC-PDVPYGGCNA-N
[SMILES]

CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@H]2CC[C@@]3(C)C(CCC4C3CC[C@]5(C)[C@H]([C@H](C[C@]45O)OC(C)=O)C6=CC(=O)OC6)C2
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Solid
[Uses]

Cardiotonic; diuretic
[Definition]

ChEBI: A steroid saponin that consists of oleandrigenin having a 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl residue attached to the oxygen function at position 3.
[Biological Activity]

Cardiac glycosideinhibits Na(+)/K(+) ATPase; potent carcinostatic cardiac glycoside.
[Safety Profile]

Poison by subcutaneous andintravenous routes. When heated to decomposition itemits acrid smoke and irritating fumes.
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

23/24/25-33-23/25
[Safety Statements ]

22-36/37/39-45
[RIDADR ]

2811
[WGK Germany ]

3
[RTECS ]

FH4585000
[Storage Class]

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
[Hazard Classifications]

Acute Tox. 2 Inhalation
Acute Tox. 2 Oral
STOT RE 2
[Hazardous Substances Data]

465-16-7(Hazardous Substances Data)
[Toxicity]

LD50 ivn-cat: 300 mg/kg MEIEDD 10,979,83
Spectrum DetailBack Directory
[Spectrum Detail]

OLEANDRIN(465-16-7)1HNMR
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