| Identification | More | [Name]
4-AMINOTHIOBENZAMIDE | [CAS]
4714-67-4 | [Synonyms]
4-AMINOTHIOBENZAMIDE
4-amino-benzenecarbothioamid
4-aminobenzenecarbothioamide
p-aminobenzothiamide
p-aminothio-benzamid
4-Amino Thiobenzamide p-Amino Thiobenzamide
PARA-AMINOTHIOBENZAMIDE
p-AminoThioBenzamide | [Molecular Formula]
C7H8N2S | [MDL Number]
MFCD00040927 | [Molecular Weight]
152.22 | [MOL File]
4714-67-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
185-190 °C | [Boiling point ]
325.6±44.0 °C(Predicted) | [density ]
1.286 | [solubility ]
DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 0.15 mg/ml | [form ]
A crystalline solid | [pka]
13.25±0.29(Predicted) | [color ]
Light yellow to yellow | [InChI]
1S/C7H8N2S/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H2,9,10) | [InChIKey]
LZJVSPPXXGXGQL-UHFFFAOYSA-N | [SMILES]
NC(=S)c1ccc(N)cc1 | [CAS DataBase Reference]
4714-67-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H317-H319 | [Precautionary statements ]
P280-P301+P312+P330-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HS Code ]
2930909899 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Sens. 1 | [Toxicity]
mouse,LD50,intraperitoneal,75mg/kg (75mg/kg),National Technical Information Service. Vol. AD691-490, |
| Hazard Information | Back Directory | [Description]
4-amino Benzthioamide is a synthetic intermediate useful for pharmaceutical synthesis. | [Uses]
3-Aminobenzothioamide is a small H2S donor. 3-Aminobenzothioamide has the potential for the research of myocardial ischemia-reperfusion injury[1][2]. | [References]
[1] Sarkar S, et al. Hydrogels for Gasotransmitter Delivery: Nitric Oxide, Carbon Monoxide, and Hydrogen Sulfide. Macromol Biosci. 2024 Jan;24(1):e2300138. DOI:10.1002/mabi.202300138
[2] Zhang Q, et al. Hydrogen sulfide releasing hydrogel for alleviating cardiac inflammation and protecting against myocardiZhang Q, et al. Hydrogen sulfide releasing hydrogel for alleviating cardiac inflammation and protecting against myocardial ischemia-reperfusion injury. J Mater Chem B. 2022 Jul 20;10(28):5344-5351.al ischemia-reperfusion injury. J Mater Chem B. 2022 Jul 20;10(28):5344-5351. DOI:10.1039/d2tb00971d |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|