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475-81-0

475-81-0 Structure

475-81-0 Structure
IdentificationBack Directory
[Name]

BOLDINE DIMETHYL ETHER
[CAS]

475-81-0
[Synonyms]

glauvent
GLAUCINE
Nsc34396
Aids011385
d-glaucine
Aids-011385
(S)-Glaucine
bromcholitin
(+)-GLAUCINE
Glaucine fumarate
BOLDINE DIMETHYL ETHER
1,2,9,10-TETRAMETHOXYAPORPHINE
1,2,9,10-tetramethoxy-6a-alpha-aporphin
1,2,9,10-tetramethoxy-6a-alpha-aporphine
4h-dibenzo(de,g)quinoline,5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl
(s)-5,6,6a7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4h-dibenzo(de,g)quinol
(S)-1,2,9,10-TETRAMETHOXY-6-METHYL-5,6,6A,7-TETRAHYDRO-4H-DIBENZO[DE,G]QUINOLINE
(S)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline
(6aS)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline
4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-, (6aS)-
[EINECS(EC#)]

207-501-5
[Molecular Formula]

C21H25NO4
[MDL Number]

MFCD00075953
[MOL File]

475-81-0.mol
[Molecular Weight]

355.43
Chemical PropertiesBack Directory
[Melting point ]

246-247℃
[alpha ]

D20 +115° (c = 3 in alc)
[Boiling point ]

488.45°C (rough estimate)
[density ]

1.166±0.06 g/cm3 (20 ºC 760 Torr)
[refractive index ]

1.5614 (estimate)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

6.35±0.20(Predicted)
[color ]

Pale Beige
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
Hazard InformationBack Directory
[Description]

Glaucine (Item No. 17338) is an analytical reference standard categorized as an antitussive. Glaucine has hallucinogenic properties. This product is intended for research and forensic applications.
[Uses]

d-Glaucine has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries.
[Definition]

ChEBI: (S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups. It has a role as a platelet aggregation inhibitor, a NF-kappaB inhibitor, an antitussive, an antibacterial agent, a muscle relaxant, an antineoplastic agent, a plant metabolite and a rat metabolite. It is an aporphine alkaloid, a polyether, an organic heterotetracyclic compound and a tertiary amino compound. It is a conjugate base of a (S)-glaucine(1+).
[References]

[1] UJVáRY I. Psychoactive natural products: overview of recent developments.[J]. Annali dell’Istituto superiore di sanita, 2014, 50 1: 12-27. DOI: 10.4415/ann_14_01_04
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
Spectrum DetailBack Directory
[Spectrum Detail]

BOLDINE DIMETHYL ETHER(475-81-0)MS
BOLDINE DIMETHYL ETHER(475-81-0)1HNMR
BOLDINE DIMETHYL ETHER(475-81-0)IR1
BOLDINE DIMETHYL ETHER(475-81-0)IR2
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