| Identification | Back Directory | [Name]
NUCIFERINE | [CAS]
475-83-2 | [Synonyms]
6a
VLT 049
Nuciferi
nuciferin
NUCIFERINE
fettuccine
Sanjoinine
Sanjoinine E
l-nuciferine
(R)-Nuciferine
(-)-nucipherine
D-(-)-Nuciferine
Lotus leaf alkali
radix bupleuri P.E
Nuciferine 475-83-2
NUCIFERINE USP/EP/BP
l-5,6-dimethoxyaporphine
(r)-1,2-dimethoxyaporphine
1,2-Dimethoxy-6aβ-aporphine
1,2-Dimethoxy-6αβ-aporphine
Lotus Leaf Extract Nuciferin
satis indigotica fort Extract
1,2-dimethoxy-6a-beta-aporphin
Nuciferine, 98%, from Lotus Leaf
Lotus Leaf Extract Powder Nuciferine
professional manufacturer Nuciferine 475-83-2
2%, 3%, 4%, 5%, 50%, 98% Lotus Leaf Extract Powder Nuciferine
1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-g)quinolin(r)-4h-dibenzo(d
(R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
(6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-diMethoxy-6-Methyl-, (6aR)-
Nuciferine
1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | [EINECS(EC#)]
618-170-5 | [Molecular Formula]
C19H21NO2 | [MDL Number]
MFCD01664592 | [MOL File]
475-83-2.mol | [Molecular Weight]
295.38 |
| Chemical Properties | Back Directory | [Melting point ]
165.5°C | [Boiling point ]
437.06°C (rough estimate) | [density ]
1.1156 (rough estimate) | [refractive index ]
1.5000 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | [form ]
powder | [pka]
7.87±0.20(Predicted) | [color ]
white to beige | [Optical Rotation]
[α]/D -145 to -165°, c = 0.5 in ethanol | [InChI]
InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1 | [InChIKey]
ORJVQPIHKOARKV-OAHLLOKOSA-N | [SMILES]
N1(C)[C@@]2([H])C3=C(C(OC)=C(OC)C=C3CC1)C1=CC=CC=C1C2 | [LogP]
2.357 (est) |
| Questions And Answer | Back Directory | [Uses]
The lotus leaf alkaloid has the effect of weight loss and lipid reduction, and can be used for content determination/identification/pharmacological experiments.
|
| Safety Data | Back Directory | [Safety Statements ]
24/25 | [RIDADR ]
UN 1544PSN1 6.1 / PGIII | [HS Code ]
29389090 | [Toxicity]
LD50 orl-rat: 280 mg/kg AIPTAK 197,261,72 |
| Hazard Information | Back Directory | [Description]
An aporphine alkaloid from Nelumbo lutea, the ba~e yields colourless crystals
when crystallized from EtOH. It is laevorotatory, the following specific rotations
having been recorded; [α] 22
D- 157.5° and - 215°. The ultraviolet spectrum has
three absorption maxima at 230, 272 and 310 mp.. Two methoxyl groups and
one methylimino group are present and the alkaloid may be characterized as the
hydrochloride, m.p. 241°C (in vacuo) and the methiodide, m.p. 177-8°C. The
optically inactive base has been synthesized and has m.p. 136-7°C, giving a
hydrochloride in the form of small colourless prisms from H20, m.p. 258°C
(dec.). | [Chemical Properties]
It is easily soluble in organic solvents with low polarity such as benzene, ether, chloroform, and halogenated alkanes. It also has good solubility in hydrophilic organic solvents such as acetone and ethanol, but has low solubility or is almost insoluble in water. It comes from the dried leaves of the lotus plant of the Nymphaeaceae family. | [Safety Profile]
Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx. | [References]
Gulland, Haworth., J. Chern. Soc., 590 (1928)
Yunusov, Konovalova, Orekhov., Bull. Soc. Chim. Fr., 70 (1940)
Arthur, Cheung., J. Chern. Soc., 2306 (1959)
Kupchan et al., Tetrahedron, 19, 227 (1963) |
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| Company Name: |
China Langchem Inc.
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| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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