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59870-68-7

59870-68-7 Structure

59870-68-7 Structure
IdentificationMore
[Name]

Glabridin
[CAS]

59870-68-7
[Synonyms]

GLABRIDIN
4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[6,5-f]chromen-3-yl]benzene-1,3-diol
GLABRIDIN (GLYCYRRHIZA GLABRA ROOT EXTRACT)
[EINECS(EC#)]

611-908-7
[Molecular Formula]

C20H20O4
[MDL Number]

MFCD03427694
[Molecular Weight]

324.37
[MOL File]

59870-68-7.mol
Chemical PropertiesBack Directory
[Melting point ]

154~155℃
[Boiling point ]

518.6±50.0 °C(Predicted)
[density ]

1.257±0.06 g/cm3(Predicted)
[Fp ]

267℃
[storage temp. ]

room temp
[solubility ]

DMSO: soluble5mg/mL, clear (warmed)
[pka]

9.66±0.40(Predicted)
[form ]

powder
[color ]

white to light brown
[BRN ]

7141956
[InChIKey]

PMPYOYXFIHXBJI-ZDUSSCGKSA-N
[CAS DataBase Reference]

59870-68-7(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[HS Code ]

29329990
Hazard InformationBack Directory
[Chemical Properties]

White to tan powder
[Uses]

Glabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative.
[Definition]

ChEBI: A member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4' and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively.
[Biochem/physiol Actions]

Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.
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