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4753-04-2

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4753-04-2 Structure

4753-04-2 Structure
IdentificationMore
[Name]

2'-CHLORO-2'-DEOXYURIDINE
[CAS]

4753-04-2
[Synonyms]

NSC 526746
2-CHLORO-2-DEOXYURIDINE
2'-CHLORO-2'-DEOXYURIDINE
Uridine, 2'-chloro-2'-deoxy-
[Molecular Formula]

C9H11ClN2O5
[MDL Number]

MFCD00057379
[Molecular Weight]

262.65
[MOL File]

4753-04-2.mol
Chemical PropertiesBack Directory
[Melting point ]

207-212 °C (decomp)
[density ]

1.67±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[pka]

9.39±0.10(Predicted)
[CAS DataBase Reference]

4753-04-2(CAS DataBase Reference)
Hazard InformationBack Directory
[Uses]

2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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