| Identification | More | [Name]
2,6-Dichloropyrazine | [CAS]
4774-14-5 | [Synonyms]
2,6-CHLORO PYRAZINE
2,6-DICHLOROPYRAZINE
2,6-dichloro-pyrazin
Pyrazine, 2,6-dichloro-
2,6-Dichloropyrazine,99%
2,6-Dichlor-pyrazin
2,6-Dichloropiperazine | [EINECS(EC#)]
225-316-8 | [Molecular Formula]
C4H2Cl2N2 | [MDL Number]
MFCD00006125 | [Molecular Weight]
148.98 | [MOL File]
4774-14-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White Powder | [Melting point ]
55-58 °C (lit.) | [Boiling point ]
122 °C / 40mmHg | [density ]
1.6445 (rough estimate) | [refractive index ]
1.6300 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Soluble in ethanol and methanol. | [form ]
Crystals or Crystalline Powder | [pka]
-3.11±0.10(Predicted) | [color ]
White to beige | [BRN ]
2439 | [InChI]
1S/C4H2Cl2N2/c5-3-1-7-2-4(6)8-3/h1-2H | [InChIKey]
LSEAAPGIZCDEEH-UHFFFAOYSA-N | [SMILES]
Clc1cncc(Cl)n1 | [LogP]
1.530 | [CAS DataBase Reference]
4774-14-5(CAS DataBase Reference) | [NIST Chemistry Reference]
2,6-Dichloropyrazine(4774-14-5) | [EPA Substance Registry System]
4774-14-5(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White Powder | [Uses]
2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. | [Uses]
Used in a synthesis of oxacalixarenes containing nitrogen heterocycles.1 | [Synthesis]
The production method of 2,6-dichloropyrazine comprises the following steps: carrying out ammoniation and cyclization reactions of raw materials comprising methyl chloroacetate, glyoxal and the like to prepare 2-hydroxypyrazine sodium, reacting 2-hydroxypyrazine sodium with phosphorous oxychloride under the catalysis action of N,N-dimethylaminopyridine to prepare 2-chloropyrazine, and chlorinating 2-chloropyrazine by chlorine under the catalysis action of triethylamine with dimethyl formamide as a solvent to prepare 2,6-dichloropyrazine. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|