ChemicalBook--->CAS DataBase List--->485799-04-0

485799-04-0

485799-04-0 Structure

485799-04-0 Structure
IdentificationMore
[Name]

6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester
[CAS]

485799-04-0
[Synonyms]

1-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]MORPHOLINE
2-(4-MORPHOLINO)PYRIDINE-5-BORONIC ACID PINACOL ESTER
2-(MORPHOLIN-4-YL)PYRIDINE-5-BORONIC ACID PINACOL ESTER
2-MORPHOLIN-5-PYRIDYLBORONIC ACID PINACOL ESTER
2-MORPHOLINE-4-YL-PYRIDINE-5-BORONIC ACID PINACOL ESTER
2-MORPHOLINOPYRIDINE-5-BORONIC ACID, PINACOL ESTER
4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-2-PYRIDINYL]MORPHOLINE
4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-MORPHOLINE
6-(MORPHOLIN-4-YL)PYRIDINE-3-BORONIC ACID PINACOL ESTER
6-MORPHOLINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER
6-MORPHOLINOPYRIDIN-3-YLBORONIC ACID PINACOL ESTER
6-(4-MORPHOLINO)PYRIDINE-3-BORONIC ACID PINACOL ESTER
4-5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylümorpholine
6-(4-Morpholinyl)pyridine-3-boronic acid pinacol ester
[Molecular Formula]

C15H25BN2O4
[MDL Number]

MFCD04039874
[Molecular Weight]

308.18
[MOL File]

485799-04-0.mol
Chemical PropertiesBack Directory
[Melting point ]

135-139 °C (lit.)
[Boiling point ]

440.9±45.0 °C(Predicted)
[density ]

1.13±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[pka]

5.58±0.10(Predicted)
[Appearance]

White to off-white Solid
[CAS DataBase Reference]

485799-04-0(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi,Xn
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[RIDADR ]

2811
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HazardClass ]

IRRITANT
[HS Code ]

2934999090
Spectrum DetailBack Directory
[Spectrum Detail]

6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester(485799-04-0)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]morpholine(485799-04-0)
[Alfa Aesar]

6-(4-Morpholinyl)pyridine-3-boronic acid pinacol ester(485799-04-0)
[Sigma Aldrich]

485799-04-0(sigmaaldrich)
Hazard InformationBack Directory
[Synthesis]

Bis(pinacolato)diboron

73183-34-3

4-(5-BROMOPYRIDIN-2-YL)MORPHOLINE

200064-11-5

6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester

485799-04-0

Pinacol ester of bisboronic acid (1.25 g, 4.92 mmol) was dissolved in DMF (10 mL) under nitrogen protection and cooled to 0 °C. KOAc (1.21 g, 12.3 mmol) and Pd(dppf)Cl2-CH2Cl2 (0.1 g, 0.123 mmol) were added sequentially. The reaction mixture was heated to 80 °C and a solution of 5-bromo-2-morpholine pyridine (1.0 g, 4.1 mmol) in DMF (10 mL) was added dropwise. After the dropwise addition, the reaction was continued to be stirred at 80 °C for 10 hours. After completion of the reaction, the solvent was removed by evaporation. The residue was dissolved in ethyl acetate and the insoluble material was removed by filtration. The filtrate was evaporated and purified by column chromatography (eluent ratio: ethyl acetate:petroleum ether = 1:4) to afford 6-(morpholin-4-yl)pyridine-3-boronic acid pinacol ester (940 mg, 79% yield).

[References]

[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 41-42
[2] Patent: WO2009/155527, 2009, A2. Location in patent: Page/Page column 136
485799-04-0 suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +8613336195806 , +8613336195806
Website: www.capot.com
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-2158073036
Website: www.dakenchem.com/
Company Name: HaBo Hong Kong Co., Limited.
Tel: +86-25-18512596065
Website: www.chemicalbook.com/ShowSupplierProductsList31287/0_EN.htm
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.chemicalbook.com/ShowSupplierProductsList1549548/0_EN.htm
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Website: www.chemicalbook.com/ShowSupplierProductsList454175/0_EN.htm
Company Name: Wuhan Chemwish Technology Co., Ltd
Tel: 027-67849912
Website: www.chemicalbook.com/ShowSupplierProductsList485773/0_EN.htm
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com
Company Name: Neostar United (Changzhou) Industrial Co., Ltd.
Tel: +86-0519-85551759 +8613506123987 , +8613506123987
Website: http://www.neostarunited.com
Company Name: Chengdu Aslee Biopharmaceuticals, Inc.
Tel: 28-85305008
Website: www.chemicalbook.com/ShowSupplierProductsList778448/0_EN.htm
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196 , +8618530059196
Website: www.chemicalbook.com/manufacturer/zhengzhou-alfa-chemical-276/
Company Name: ANHUI WITOP BIOTECH CO., LTD
Tel: +8615255079626 , +8615255079626
Website: www.chemicalbook.com/ShowSupplierProductsList418627/0_EN.htm
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250 , +86-15129568250
Website: https://www.dideu.com
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
Tel: +86-0571-88938639 +8617705817739 , +8617705817739
Website: www.dycnchem.com/
Company Name: CD Chemical Group Limited
Tel: +8615986615575 , +8615986615575
Website: http://www.codchem.com/
Company Name: Alfa Chemistry
Tel: +1-5166625404;
Website: https://www.alfa-chemistry.com/
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418684 +8618949823763 , +8618949823763
Website: www.tnjchem.com
Company Name: GIHI CHEMICALS CO.,LIMITED
Tel: +8618058761490 , +8618058761490
Website: www.gihichem.com/
Tags:485799-04-0 Related Product Information
3731-59-7 96-33-3 24602-86-6 110-86-1 142-77-8 10497-05-9 4856-95-5 329214-79-1 827614-64-2 1692-25-7 7440-42-8 485799-04-0

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.