| Identification | More | [Name]
3-CHLORO-5-FLUOROANILINE | [CAS]
4863-91-6 | [Synonyms]
3-CHLORO-5-FLUOROANILINE
BUTTPARK 44\01-96
3-Chloro-5-fluoroaniline98%
3-fluoro-5-chloroaniline | [Molecular Formula]
C6H5ClFN | [MDL Number]
MFCD03407962 | [Molecular Weight]
145.56 | [MOL File]
4863-91-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear orange liquid | [Boiling point ]
98C/19Torr | [density ]
1.45 | [refractive index ]
1.561-1.563
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
Liquid | [pka]
2.52±0.10(Predicted) | [color ]
Clear light yellow to orange | [InChI]
1S/C6H5ClFN/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2 | [InChIKey]
LPIFAHAICWJMRR-UHFFFAOYSA-N | [SMILES]
Nc1cc(F)cc(Cl)c1 | [CAS DataBase Reference]
4863-91-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
2810 | [WGK Germany ]
WGK 3 | [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [HazardClass ]
TOXIC | [HS Code ]
29214200 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Clear orange liquid | [Uses]
3-Chloro-5-fluoroaniline(4863-91-6) is an aniline derivative with chlorine and fluorine substituents at positions 3 and 5, respectively, which can be used as a reagent for chemical reactions, as a raw material for organic synthesis, and as a component of pharmaceutical intermediates. It is widely used in the synthesis of active pharmaceutical ingredients (APIs), especially antiviral compounds against the influenza A (H1N1) virus. It is also used in the synthesis of glucocorticoid receptor agonists for the treatment of inflammation. In addition, the presence of chloro and fluorine substituents in 3-chloro-5-fluoroaniline allows for further functionalisation such as palladium-catalysed carbon-carbon coupling and nucleophilic aromatic substitution.
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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