| Identification | Back Directory | [Name]
CHRYSOERIOL | [CAS]
491-71-4 | [Synonyms]
chryseriol
Chrysoriol
CHRYSOERIOL
Chebi:16514
Luteolin 3'-
CHRYSOERIOL hplc
3’-methoxyapigenin
3’-o-methyluteolin
Chrysoeriol (>90%)
3'-o-Methylluteolin
CHRYSOERIOL WITH HPLC
Luteolin 3'-methyl ether
574TRIHYDROXY3METHOXYFLAVONE
4',5,7-TRIHYDROXY-3'-METHOXYFLAVON
4',5,7-TRIHYDROXY-3'-METHOXYFLAVONE
3'-METHOXY-5,7,4'-TRIHYDROXYFLAVONE
3'-Methoxy-4',5,7-trihydroxyflavone
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4h-1-benzopyran-4-on
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)- | [EINECS(EC#)]
207-742-6 | [Molecular Formula]
C16H12O6 | [MDL Number]
MFCD00016780 | [MOL File]
491-71-4.mol | [Molecular Weight]
300.26 |
| Chemical Properties | Back Directory | [Melting point ]
>300°C (dec.) | [Boiling point ]
574.3±50.0 °C(Predicted) | [density ]
1.512±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated and Sonicated) | [form ]
Solid | [pka]
6.49±0.40(Predicted) | [color ]
Yellow to Very Dark Yellow | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C16H12O6/c1-21-14-4-8(2-3-10(14)18)13-7-12(20)16-11(19)5-9(17)6-15(16)22-13/h2-7,17-19H,1H3 | [InChIKey]
SCZVLDHREVKTSH-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=C(O)C(OC)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1 | [LogP]
2.229 (est) |
| Hazard Information | Back Directory | [Uses]
A methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000). | [Definition]
ChEBI: The 3'-O-methyl derivative of luteolin. | [in vivo]
Chrysoeriol (1 mg/ear; external application) improves ear edema induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in mice, and inhibits the JAK2/STAT3 and IκB/p65 NF-κB pathways to improve inflammation[3].
| [target]
ERK | p38 | Akt | PI3K | mTOR | p21 | AhR | P450 (e.g. CYP17) | NOS | NF-kB | AP-1 | ROS | Potassium Channel |
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