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491-71-4

491-71-4 Structure

491-71-4 Structure
IdentificationBack Directory
[Name]

CHRYSOERIOL
[CAS]

491-71-4
[Synonyms]

chryseriol
Chrysoriol
CHRYSOERIOL
Chebi:16514
Luteolin 3'-
CHRYSOERIOL hplc
3’-methoxyapigenin
3’-o-methyluteolin
Chrysoeriol (>90%)
3'-o-Methylluteolin
CHRYSOERIOL WITH HPLC
Luteolin 3'-methyl ether
574TRIHYDROXY3METHOXYFLAVONE
4',5,7-TRIHYDROXY-3'-METHOXYFLAVON
4',5,7-TRIHYDROXY-3'-METHOXYFLAVONE
3'-METHOXY-5,7,4'-TRIHYDROXYFLAVONE
3'-Methoxy-4',5,7-trihydroxyflavone
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4h-1-benzopyran-4-on
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-
[EINECS(EC#)]

207-742-6
[Molecular Formula]

C16H12O6
[MDL Number]

MFCD00016780
[MOL File]

491-71-4.mol
[Molecular Weight]

300.26
Chemical PropertiesBack Directory
[Melting point ]

>300°C (dec.)
[Boiling point ]

574.3±50.0 °C(Predicted)
[density ]

1.512±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
[form ]

Solid
[pka]

6.49±0.40(Predicted)
[color ]

Yellow to Very Dark Yellow
[Stability:]

Hygroscopic
[InChI]

InChI=1S/C16H12O6/c1-21-14-4-8(2-3-10(14)18)13-7-12(20)16-11(19)5-9(17)6-15(16)22-13/h2-7,17-19H,1H3
[InChIKey]

SCZVLDHREVKTSH-UHFFFAOYSA-N
[SMILES]

C1(C2=CC=C(O)C(OC)=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1
[LogP]

2.229 (est)
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

A methoxyflavonoid that selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. A metabolite of Luteolin (L475000).
[Definition]

ChEBI: The 3'-O-methyl derivative of luteolin.
[in vivo]

Chrysoeriol (1 mg/ear; external application) improves ear edema induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in mice, and inhibits the JAK2/STAT3 and IκB/p65 NF-κB pathways to improve inflammation[3].

[target]

ERK | p38 | Akt | PI3K | mTOR | p21 | AhR | P450 (e.g. CYP17) | NOS | NF-kB | AP-1 | ROS | Potassium Channel
Spectrum DetailBack Directory
[Spectrum Detail]

CHRYSOERIOL(491-71-4)1HNMR
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