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4984-22-9

4984-22-9 Structure

4984-22-9 Structure
IdentificationMore
[Name]

(R)-(-)-1-METHOXY-2-PROPANOL
[CAS]

4984-22-9
[Synonyms]

(R)-(-)-1-METHOXY-2-PROPANOL
(R)-1-METHOXY-2-PROPANOL
(R)-2-HYDROXY-1-METHOXYPROPANE
(R)-(+)-PROPYLENE GLYCOL 1-METHYL ETHER
(R)-(-)-1-Methoxy-2-propanol, 98+%
(R)-(-)-1-METHOXY-2-PROPANOL 98%
(R)-1-METHOXY-2-PROPANOL,95+%
[EINECS(EC#)]

628-460-3
[Molecular Formula]

C4H10O2
[MDL Number]

MFCD01632587
[Molecular Weight]

90.12
[MOL File]

4984-22-9.mol
Chemical PropertiesBack Directory
[Appearance]

Colorless to light yellow liqui
[Melting point ]

-97 °C
[Boiling point ]

119-121 °C (lit.)
[density ]

0.921 g/mL at 20 °C(lit.)
[refractive index ]

n20/D 1.403
[Fp ]

33 °C
[storage temp. ]

Flammables area
[form ]

Liquid
[pka]

14.49±0.20(Predicted)
[color ]

Clear colorless
[Optical Rotation]

[α]20/D 22±2°, c = 10% in chloroform
[BRN ]

1718941
[InChI]

InChI=1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3/t4-/m1/s1
[InChIKey]

ARXJGSRGQADJSQ-SCSAIBSYSA-N
[SMILES]

C(OC)[C@H](O)C
[CAS DataBase Reference]

4984-22-9(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Warning
[Hazard statements ]

H320-H336-H226
[Precautionary statements ]

P501-P261-P240-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P303+P361+P353-P304+P340+P312-P403+P233-P403+P235-P405
[Hazard Codes ]

F,Xn
[Risk Statements ]

R10:Flammable.
R15:Contact with water liberates extremely flammable gases.
[Safety Statements ]

S24:Avoid contact with skin .
S43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add-Never use water) .
S7/8:Keep container tightly closed and dry .
[RIDADR ]

UN 3092 3/PG 3
[WGK Germany ]

1
[HazardClass ]

3
[PackingGroup ]

[HS Code ]

29051990
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Flam. Liq. 3
Hazard InformationBack Directory
[Chemical Properties]

Colorless to light yellow liqui
[Uses]

(R)-(-)-1-Methoxy-2-propanol can be used as a reactant to prepare:
  • (S)-3-(ethoxycarbonyl)-5-((1-methoxypropan-2-yl)oxy)benzoic acid, a key intermediate to synthesize phenylethyl benzamide derivatives, which can be used as glucokinase activators.
  • Chiral pyrazolopyrimidinone derivatives as potential phosphodiesterase enzyme (PDE5) inhibitors.
  • Aryl or alkyl ethers via etherification reaction.

[General Description]

(R)-(-)-1-Methoxy-2-propanol is a chiral secondary alcohol. It is formed during the hydrolysis of (R)-1-methoxy-2-propyl-acetate in the presence of Candida antarctica lipase B.
Spectrum DetailBack Directory
[Spectrum Detail]

(R)-(-)-1-METHOXY-2-PROPANOL(4984-22-9)MS
(R)-(-)-1-METHOXY-2-PROPANOL(4984-22-9)1HNMR
(R)-(-)-1-METHOXY-2-PROPANOL(4984-22-9)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

(R)-(-)-1-Methoxy-2-propanol, 98+%(4984-22-9)
[Sigma Aldrich]

4984-22-9(sigmaaldrich)
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