| Identification | Back Directory | [Name]
KRP-203 | [CAS]
509088-69-1 | [Synonyms]
KRP-203
KRP-203 HCl
KRP-203 (hydrochloride)
Mocravimod hydrochloride
Mocravimod dihydrochloride
2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol
2-AMINO-2-[2-[2-CHLORO-4-[[3-(PHENYLMETHOXY)PHENYL]THIO]PHENYL]ETHYL]-1,3-PROPANEDIOL HCL
2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chloro-phenethyl)propane-1,3-diol hydrochloride
2-Amino-2-(2-(4-(3-benzyloxyphenylthio)-2-chlorophenyl)ethyl)-1,3-propanediol hydrochloride
KRP203/2-AMino-2-(2-(4-(3-benzyloxyphenylthio)-2-chlorophenyl)ethyl)-1,3-propanediol hydrochloride
2-amino-2-[2-[2-chloro-4-(3-phenylmethoxyphenyl)sulfanylphenyl]ethyl]propane-1,3-diol,hydrochloride
2-Amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol Hydrochloride | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C24H27Cl2NO3S | [MDL Number]
MFCD09952233 | [MOL File]
509088-69-1.mol | [Molecular Weight]
480.45 |
| Hazard Information | Back Directory | [Uses]
A novel immunomodulator | [Uses]
A novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. | [Uses]
A novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. Immunosuppressant. | [in vivo]
Mocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R / Mice[1].
Mocravimod hydrochloride (KRP-203) (orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection in mHC-disparate rat heart allografts[2].
| Animal Model: | Inbred male DA (MHC haplotype: RT1a) rats[2] | | Dosage: | 0.1 and 1 mg/kg | | Administration: | Orally; daily; for 100 days
| | Result: | Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts.
|
| [storage]
Store at -20°C |
|
|