| Identification | Back Directory | [Name]
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy- | [CAS]
512177-31-0 | [Synonyms]
187381
CCR2-RA
4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1H-pyrrol-2(5H)-one
4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one
4-Acetyl-1-(4-Chloro-2-Fluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One
2H-Pyrrol-2-one, 4-acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy- | [Molecular Formula]
C18H19ClFNO3 | [MOL File]
512177-31-0.mol | [Molecular Weight]
351.8 |
| Hazard Information | Back Directory | [Uses]
CCR2-RA is a allosteric antagonist of chemokine (C-C motif) receptor 2 (CCR 2), and it can be used in cancer research[1]. | [IC 50]
CCR2 | [References]
[1] Lisa S den Hollander, et al. CC chemokine receptor 2 is allosterically modulated by sodium ions and amiloride derivatives through a distinct sodium ion binding site. Biochem Pharmacol. 2024 Nov:229:116464. DOI:10.1016/j.bcp.2024.116464 |
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