| Identification | More | [Name]
Canthaxanthin | [CAS]
514-78-3 | [Synonyms]
4,4'-DIKETO-BETA-CAROTENE
4',4-DIOXO-B-CAROTENE
B,B-CAROTENE-4,4'DIONE
BETA,BETA-CAROTENE-4,4'-DIONE
BETA,BETA'-CAROTIN-4,4'-DIONE
CANTHAXANTHIN
CANTHAXANTHINE
CANTHAXANTHIN, TRANS-
E 161 G
FOOD ORANGE 8
ROXANTHIN
TRANS-CANTHAXANTHIN
4’-dione,all-trans-.beta.-Carotene-4
all-trans,beta-carotene-4,4’-dione
all-trans-beta-carotene-4’-dione
c.i.foodorange8
cantaxanthin
carophyllred
l-orange7
orobronze | [EINECS(EC#)]
208-187-2 | [Molecular Formula]
C40H52O2 | [MDL Number]
MFCD00016364 | [Molecular Weight]
564.84 | [MOL File]
514-78-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
217～218℃ | [Boiling point ]
717.0±40.0 °C(Predicted) | [density ]
1.003±0.06 g/cm3(Predicted) | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly) | [form ]
neat | [color ]
Very Dark Red to Black | [biological source]
synthetic | [λmax]
λ: 465 nm±5 nm Amax | [Merck ]
13,1758 | [BRN ]
1898520 | [Stability:]
Light Sensitive | [Major Application]
food and beverages | [Cosmetics Ingredients Functions]
COLORANT | [InChIKey]
FDSDTBUPSURDBL-DKLMTRRASA-N | [SMILES]
CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C(=O)CCC1(C)C)\C=C\C=C(C)\C=C\C2=C(C)C(=O)CCC2(C)C | [LogP]
9.526 (est) | [Uses]
Canthaxanthin is a synthetic red colorant that is the carotenoid of
most intense red color. it is available in oil-soluble, oil-dispersible,
and water-dispersible forms. it has fair ph, heat, light, and chemical
stability with a low tinctorial strength. unlike the carotenoids beta-
carotene and beta-apo-8-carotenal, it does not possess vitamin a
activity. maximum usage level is 66 ppm. uses include carbonated
soft drinks, salad dressing, and spaghetti sauce. | [CAS DataBase Reference]
514-78-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard statements ]
H412 | [Precautionary statements ]
P273-P501 | [WGK Germany ]
nwg | [RTECS ]
FI0330000 | [Storage Class]
11 - Combustible Solids | [Safety Profile]
When heated to
decomposition it emits acrid smoke and
irritating fumes. |
| Hazard Information | Back Directory | [Hazard]
Oral intake may cause loss of night vision. | [Application]
Canthaxanthin is widely used as a feed additive to improve skin and yolk color in poultry. | [Definition]
ChEBI: A carotenone that consists of beta,beta-carotene bearing two oxo substituents at positions 4 and 4'. | [Brand name]
Apotrin;Phenoro. | [World Health Organization (WHO)]
Canthaxanthin, a naturally-occurring carotenoid with a deep redorange
colour, is widely used as a food colouring agent. Since the mid-1970s it has
been included in oral 'artificial suntan' preparations. It is also available in
preparations used in the treatment of certain photodermatoses. By the mid-1980s
its use in such preparations had been associated with the accumulation of
crystalline deposits in the retina. Reported functional changes relating to dark
adaptation have been of marginal clinical significance and largely reversible.
Nevertheless, this has led to the withdrawal of artificial suntan preparations
containing canthaxanthin by several regulatory authorities. Preparations for
treatment of photodermatoses remain available in some but not all of these
countries. | [General Description]
Canthaxanthin (red diketocarotenoid or 4, 4′-diketo-β-carotene), is a common xanthophyll found naturally in microorganisms and marine organisms, as well as in certain animals. It acts as an antioxidant in living organisms. The potential antioxidant activity of canthaxanthin is due to the presence of conjugated double bonds in its structure. It finds applications in various fields including poultry, fishery, cosmetics, medicine, and pharmaceuticals. In food industries, canthaxanthin can be used as a coloring agent. | [storage]
Store at -20°C, protect from light, stored under nitrogen,unstable in solution, ready to use. | [Properties and Applications]
yellow light pink to red yellow light. | [Purification Methods]
Purify canthaxanthin by chromatography on a column of deactivated alumina or magnesium oxide, or on a thin layer plate of silica gel G (M |
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Sigma-Aldrich
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