ChemicalBook--->CAS DataBase List--->517-28-2

517-28-2

517-28-2 Structure

517-28-2 Structure
IdentificationBack Directory
[Name]

Hematoxylin
[CAS]

517-28-2
[Synonyms]

C.I.75290
nci-c55889
Nsc 270085
bematoxylin
h(a)ematine
Hematoxylin
Homaeoxylin
hematoxyline
hydroxybrazilin
Natural Black 1
HAEMATOXYLIN(RG)
Hematoxylin ,95%
CAP PE BLACK DIN 61
HEMATOXYLIN, GILL II
GILLS II HAEMATOXYLIN
HEMATOXYLIN INDICATOR
HEMATOXYLIN CERTIFIED
Hematoxylin, pure, 85%
Hematoxylin, 85%, pure
GILL'S HEMATOXYLIN NO 2
HEMATOXYLIN, GILL'S NO 2
Hematoxylin, H & E Stain
HEMATOXYLIN STAIN, GILL 2
HAEMATOXYLIN (C.I. 75290)
abcolhematoxylin-certified
HEMATOXYLIN FOR MICROSCOPY
HematoxylinStain`Certified`
Hematoxylin, 96% dry weight
Hematoxylin,Natural Black 1
HeMatoxylin(Hydroxybrazilin)
Haematoxylin(Harris)Solution
Hematoxylin,90%,pure,certified
HEMATOXYLIN STAIN C.I.No 75290
HEMATOXYLIN SOLUTION GILL NO 2
GILL 2 METHOD HEMATOXYLIN STAIN
GILL HEMATOXYLIN SOLUTION NO II
Haematoxylin(Delafield)Solution
HEMATOXYLIN (C.I. 75290) CRYST.
Hematoxylin for Biological Stain
GILL'S HEMATOXYLIN SOLUTION NO 2
Haematoxylin(Ehrlich)AcidSolution
HEMATOXYLIN, 90%, CERTIFIED, PURE
Hematoxylin, certified, pure, 90%
HeMatoxylin, 85%, pure, certified
Haematoxalin(Heidenhain'SNo1-Iron)
Haematoxylin(WeigertB-Iron)Solution
HematoxylinStainCertified-C.I.75290
HEMATOXYLIN, CERTIFIED (C.I. 75290)
CAP DIN 45 FOR GLASS BOTTLE NO PTFE
HaematoxylinPhosphotungstic(Mallory)
Haematoxylin(Heidenhain'SNo2)Solution
CAP DIN 45 FOR GLASS BOTTLE WITH PTFE
Hematoxylin, C.I. 75290, pH indicator
HEMATOXYLIN C.I. 75290 BIOLOGICAL STAIN
Hematoxylin, H & E Stain, For Microscopy
Hematoxylin hydrate (dry wt.), water ca 6%
CI 75290, Hydroxybraslin, Natural Black 1
Hematoxylin cryst. (C.I. 75290) for microscopy
Hematoxylin hydrate, 96% (dry wt.), water ca 6%
HEMATOXYLIN HYDRATE (DRY WT. BASIS), WATER CA 6%
HEMATOXYLIN C.I. 75290 CERTIFIED (NATURAL BLACK 1)
Hematoxylin hydrate, 96% (dry wt. basis), water ca 6%
Hematoxylin hydrate,pure,high purity biological stain
Hematoxylin hydrate, high purity biological stain, pure
CI 75290, Hydroxybraslin, Natural Black 1, Haematoxylin
HeMatoxylin hydrate, high purity biological stain, pure 25GR
7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol
2-d)pyran-3,4,6a,9,10(6h)-pentol,7,11b-dihydro-benz(b)indeno(
4,6a,9,10(6h)-pentol,7,11b-dihydro-2-d)pyran-cis-(+)-benz(b)indeno(
4,6a,9,10(6h)-pentol,7,11b-dihydro-2-d]pyran-cis-(++)-benz[b]indeno[
[7,11b]-Dihydrobenz [b] indeno [1,2-d] pyran-3,4,6α,9,10-[6H]-pentol
4,6a,9,10(6h)-pentol,7,11b-dihydro-2-d)pyran-(6as-cis)-benz(b)indeno(
2-d]pyran-3,4,6a,9,10(6H)-pentol,7,11b-dihydro-,cis-(+)-Benz[b]indeno[1
Benzbindeno1,2-dpyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, (6aS,11bR)-
Hematoxylin 7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol
Benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6h)-pentol, 7,11b-dihydro, (6as-cis)-
(1S,10R)-8-oxatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2,4,6,12,14,16-hexaene-5,6,10,14,15-pentol
[EINECS(EC#)]

208-237-3
[Molecular Formula]

C16H14O6
[MDL Number]

MFCD00283323
[MOL File]

517-28-2.mol
[Molecular Weight]

302.28
Chemical PropertiesBack Directory
[Appearance]

light brown crystals or powder
[Melting point ]

200 °C (dec.)(lit.)
[Boiling point ]

363.32°C (rough estimate)
[bulk density]

500kg/m3
[density ]

1.2514 (rough estimate)
[vapor pressure ]

0-0Pa at 20-25℃
[refractive index ]

1.4600 (estimate)
[storage temp. ]

Store at RT.
[solubility ]

Soluble in 95% ethanol(1 mg/mL).
[Colour Index ]

75290
[form ]

Powder/Solid
[pka]

6.7(at 25℃)
[color ]

Yellow to Brown
[PH Range]

Red (0.0) to yellow (1.0);Pale yellow (5.0) to violet (6.0)
[Stability:]

Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents.
[Optical Rotation]

77.5°(C=0.01g/mL, MEOH, 20°C, 589nm)
[Water Solubility ]

SOLUBLE IN HOT WATER
[Sensitive ]

Light Sensitive
[λmax]

292nm, 445nm, 560nm
[Merck ]

14,4637
[BRN ]

91399
[Major Application]

Plasma displays, textiles, hair dyes, identifying fresh and stale rice, diag-nosing cancer progression, detecting nosing cancer progression, cervical disease, central nervous system malfunctions, detecting genes, breast cancer, collagen in a tissue sample, apoptosis, demyelinating diseases, antigens, treatment of age-related macular degeneration, burns, prostate cancer, diabetesand obesity, viral diseases, neoplasms, peripheral neural and vascular ailments, skin disorders, biotechnological applications, reference standard materials for cytology, histology andimmunohistochemistry
[InChI]

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1
[InChIKey]

WZUVPPKBWHMQCE-UHFFFAOYSA-N
[SMILES]

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O
[LogP]

0.3 at 30℃ and pH6.9
[Uses]

Colorant in inks, biological stains.
[CAS DataBase Reference]

517-28-2
[EPA Substance Registry System]

Benz[b]indeno[1, 2-d]pyran-3,4,6a,9,10(6H)- pentol, 7,11b-dihydro-, (6aS,11bR)-(517-28-2)
Hazard InformationBack Directory
[Chemical Properties]

light brown crystals or powder
[General Description]

White to yellowish crystals that redden on exposure to light.
[Air & Water Reactions]

Soluble in hot water, slightly water soluble in cold .
[Reactivity Profile]

Sensitive to light. .
[Hazard]

May be carcinogenic.
[Definition]

ChEBI: (+)-haematoxylin is a haematoxylin. It is an enantiomer of a (-)-haematoxylin.
[Biological Activity]

Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells. Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.
[storage]

Store at -20°C
[Purification Methods]

Hematoxylin recrystallises from H2O (as trihydrate) in white-yellow crystals which become red on exposure to light and then melt at 100-120o. It has been recrystallised from Me2CO/*C6H6. It has been recrystallised as well from dilute aqueous NaHSO3 until colourless and is soluble in alkali, borax and glycerol. Store it in the dark below 0o. [Morsingh & Robinson Tetrahedron 26 182 1970, Dann & Hofmann Chem Ber 98 1498 1955, Beilstein 17/8 V 469.]
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

22-36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

2
[RTECS ]

MH7875000
[TSCA ]

Yes
[REACH Registrations]

Active
[HS Code ]

32030019
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
[Hazardous Substances Data]

517-28-2(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Ethyl acetate-->Methanol-->Diethyl ether-->Petroleum ether-->Acetone
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Hematoxylin(517-28-2).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Hematoxylin(517-28-2)1HNMR
Hematoxylin(517-28-2)IR1
Hematoxylin(517-28-2)IR2
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