| Identification | Back Directory | [Name]
7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID | [CAS]
528583-91-7 | [Synonyms]
17(R)-RVD1
17(R)-RESOLVIN D1
OIWTWACQMDFHJG-BJEBZIPWSA-N
7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID
4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)- | [Molecular Formula]
C22H32O5 | [MDL Number]
MFCD11976905 | [MOL File]
528583-91-7.mol | [Molecular Weight]
376.49 |
| Chemical Properties | Back Directory | [Boiling point ]
609.2±55.0 °C(Predicted) | [density ]
1.101±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -80°C | [solubility ]
DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml | [pka]
4.58±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
17(R)-Resolvin D1 is an exhibitor of a dose-dependent reduction in leukocyte infiltration.is used in methods for predicting patient response to disease-modifying antirheumatic drug (DMARD). | [Definition]
ChEBI: Aspirin-triggered resolvin D1 is a member of the class of resolvins that consists of docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid carrying three hydroxy substituents at positions 7, 8, and 17 (the 7S,8R,17S-stereoisomer). It has a role as an anti-inflammatory agent, an antiviral agent, an analgesic, a TGFbeta receptor antagonist, a nephroprotective agent, an anti-allergic agent and a human xenobiotic metabolite. It is a resolvin, a secondary allylic alcohol and a hydroxy polyunsaturated fatty acid. |
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