ChemicalBook--->CAS DataBase List--->54240-36-7

54240-36-7

54240-36-7 Structure

54240-36-7 Structure
IdentificationBack Directory
[Name]

Mabuterolhydrochloride
[CAS]

54240-36-7
[Synonyms]

D01589
KF 868
Broncholin
MabuterolHCl
Broncholin (tn)
KF 868 (pharmaceutical)
Mabuterol hydrochloride
dl-Mabuterol hydrochloride
Mabuterol Monohydrochloride
Mabuterol hydrochloride (jan)
Mabuterol hydrochloride solution,100ppm
1-[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol hydrochloride
Benzenemethanol, 4-amino-3-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-, monohydrochloride (9CI)
[Molecular Formula]

C13H18ClF3N2O.HCl
[MDL Number]

MFCD00941398
[MOL File]

54240-36-7.mol
[Molecular Weight]

347.2
Chemical PropertiesBack Directory
[Melting point ]

205-206 °C
[solubility ]

Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly)
[form ]

neat
[Stability:]

Hygroscopic
[Major Application]

forensics and toxicology
pharmaceutical (small molecule)
[InChI]

1S/C13H18ClF3N2O.ClH/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7;/h4-5,10,19-20H,6,18H2,1-3H3;1H
[InChIKey]

MMCDXJOMPMIKGP-UHFFFAOYSA-N
[SMILES]

Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(c1)C(F)(F)F
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
[HS Code ]

29221990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
[Toxicity]

dog,LD50,intravenous,27500ug/kg (27.5mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: DYSPNEA,Arzneimittel-Forschung. Drug Research. Vol. 34, Pg. 1680, 1984.
Hazard InformationBack Directory
[Description]

Mabuterol hydrochloride i s a β2-selective adrenergic agonist closely related to clenbuterol, and useful in the treatment of chronic bronchial asthma, bronchitis, and emphysema. Its oral potency and duration of action are reported to exceed those of salbutamol.
[Originator]

Dr. Karl Thomae (W. Germany)
[Uses]

Mabuterol Hydrochloride is an acidic salt of Mabuterol (M104000). Mabuterol is a β2-adrenergic agonist, used as a bronchodilator/antiasthmatic.
[Definition]

ChEBI: Mabuterol hydrochloride is a member of (trifluoromethyl)benzenes.
[Brand name]

BRONCHOLIN
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