| Identification | More | [Name]
Procaterol hydrochloride | [CAS]
81262-93-3 | [Synonyms]
PROCATEROL HYDROCHLORIDE HEMIHYDRATE
PROCATEROL HCL HEMIHYDRATE
(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone hydrochloride
Procaterol hydrochloride | [EINECS(EC#)]
263-763-0 | [Molecular Formula]
C16H25ClN2O4 | [MDL Number]
MFCD00872222 | [Molecular Weight]
344.83 | [MOL File]
81262-93-3.mol |
| Questions And Answer | Back Directory | [Synthesis]
Procaterol hydrochloride hemihydrate was prepared from 8-hydroxyquinoline via oxidation, acylation, hydrolysis, amination, and reduction. The synthetic process is simple, with an overall yield of 30%. The specific reaction process is as follows:  |
| Hazard Information | Back Directory | [Uses]
Procaterol hydrochloride can be used as short-acting β2-adrenergic receptor agonist used to treat asthma.
| [Uses]
Short-acting β2-adrenergic receptor agonist used to treat asthma. | [Brand name]
Pro-Air (Parke-Davis). | [in vivo]
Procaterol hydrochloride hemihydrate (1, 3 or 10 μg/mL, inhaled administration) inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation[2].
Procaterol hydrochloride hemihydrate (0.1 mg/kg, i.p.) completely abolishes both the Mch-induced cough in conscious guinea pigs[3].
| Animal Model: | Allergic inflammatory guinea-pig model[2] | | Dosage: | 1, 3 or 10 μg/mL | | Administration: | Inhaled administration | | Result: | Inhibited histamine-induced airflow obstruction and microvascular leakage. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
China Langchem Inc.
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0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
Jinan Putubio Tech Co., Ltd.
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| Telephone: |
+86 (531) 8099-2215 |
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www.chemicalbook.com/ShowSupplierProductsList16923/0_EN.htm |
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