ChemicalBook--->CAS DataBase List--->81262-93-3

81262-93-3

81262-93-3 Structure

81262-93-3 Structure
IdentificationMore
[Name]

Procaterol hydrochloride
[CAS]

81262-93-3
[Synonyms]

PROCATEROL HYDROCHLORIDE HEMIHYDRATE
PROCATEROL HCL HEMIHYDRATE
(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone hydrochloride
Procaterol hydrochloride
[EINECS(EC#)]

263-763-0
[Molecular Formula]

C16H25ClN2O4
[MDL Number]

MFCD00872222
[Molecular Weight]

344.83
[MOL File]

81262-93-3.mol
Chemical PropertiesBack Directory
[Melting point ]

193-197° (dec)
[storage temp. ]

Refrigerator, Under Inert Atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
[CAS DataBase Reference]

81262-93-3(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Toxicity]

LD50 of the hydrochloride in male rats (mg/kg): 2600 orally, 80 i.v. (Nakagawa)
Hazard InformationBack Directory
[Uses]

Procaterol hydrochloride can be used as short-acting β2-adrenergic receptor agonist used to treat asthma.
[Uses]

Short-acting β2-adrenergic receptor agonist used to treat asthma.
[Brand name]

Pro-Air (Parke-Davis).
[in vivo]

Procaterol hydrochloride hemihydrate (1, 3 or 10 μg/mL, inhaled administration) inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation[2].
Procaterol hydrochloride hemihydrate (0.1 mg/kg, i.p.) completely abolishes both the Mch-induced cough in conscious guinea pigs[3].

Animal Model:Allergic inflammatory guinea-pig model[2]
Dosage:1, 3 or 10 μg/mL
Administration:Inhaled administration
Result:Inhibited histamine-induced airflow obstruction and microvascular leakage.
Spectrum DetailBack Directory
[Spectrum Detail]

Procaterol hydrochloride(81262-93-3)1HNMR
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