| Identification | Back Directory | [Name]
Nizofenone | [CAS]
54533-85-6 | [Synonyms]
EkonN Y-9179 Nizofenone Midafenone Nizofenone fumarate Nizofenone USP/EP/BP 1-[2-(2-Chlorobenzoyl)-4-nitrophenyl]-2-(diethylaminomethyl)-1H-imidazole 2'-Chloro-2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrobenzophenone (2-chlorophenyl)-[2-[2-(diethylaminomethyl)-1-imidazolyl]-5-nitrophenyl]methanone (2-Chlorophenyl)[2-[2-(diethylamino)methyl]-1H-imidazol-1-y1]-5-nitmphenyl]methanone (2-Chlorophenyl)[2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrophenyl]methanone Methanone, (2-chlorophenyl)[2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrophenyl]- | [Molecular Formula]
C21H21ClN4O3 | [MDL Number]
MFCD00864693 | [MOL File]
54533-85-6.mol | [Molecular Weight]
412.87 |
| Chemical Properties | Back Directory | [Melting point ]
75-76° | [Boiling point ]
609.7±65.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
8.75±0.25(Predicted) |
| Hazard Information | Back Directory | [Description]
Nizofenzone fumarate is a potent antianoxic agent reported of benefit to geriatric and
stroke patients. In animal models nizofenzone is reported to have protective effects against
anoxia, global ischemia or other conditions resulting from cerebral infarction. It is also
claimed to be a sedative and anticonvulsant. | [Chemical Properties]
Obtained as pale yellow crystals from isopropyl ether, melting point 75-76°C. Nizofenone Fumarate (C21H21ClN4O3?C4H4O4). [54533-86-7]. Obtained as pale yellow crystals from isopropyl ether, melting point 157-158°C. Acute toxicity LD50 for male and female mice, male and female rats (mg/kg): 495, 504, 1711, 1580 oral; 62, 70, 63, 65 intravenous; 270, 278, 1830, 1629 subcutaneous. | [Originator]
Yoshitomi (Japan) | [Definition]
ChEBI: Nizofenone is a member of benzophenones. | [Brand name]
Ekonal |
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| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
|